The Infectious Disease: Measles Virus
ABSTRACT
Measles is an infectious disease. The measles virus if from the family paramyxoviridae and genus mobilivirus. Measles infection presents with symptoms that include fever, coryza, cough, conjunctivitis and maculopapular rashes (Koplik's spots). Measles causes temporary suppression of the immune system, giving rise to secondary infections in patients. A person infected with measles will recover within three weeks if the infection is not complicated. Complications that can arise from measles infection include Subacute sclerosing panencephalitis (SSPE) , a disease which affects the central nervous system. An infected person that recovers from measles usually becomes immune to the disease for life.
The World Health Organization has adopted measles eradication goals, particularly after the successful eradication of naturally- occurring smallpox in 1977. This goal will most likely be achieved once the major challenges causing difficulty is overcome. These include the lack of effective vaccine delivery methods to rural areas and the inadequate number of trained medical personnel to efficiently administer these vaccines, as well as poor surveillance and undereporting of cases.
This review aims at appraising the current …show more content…
The causative agent is known as measles virus (MeV) . MeV is a negative-sense, non-segmented, single-stranded enveloped RNA virus from the family Paramyxoviridae and genus Morbillivirus. It measures approximately 15.9 kb (5,6,7). The MeV particle is pleomorphic and its nucleocapsid has helical symmetry. The envelope contains two virally coded glycoproteins: The F (fusion) protein and hemagglutinin (H), which is an attachment protein (a glycoprotein that binds to receptors on the host cell). Together, these two mediate viral entry. The nucleoprotein (N) encapsidates the viral genome and is the most abundant viral protein in the virion and in infected cells
Measles is an infectious disease. The measles virus if from the family paramyxoviridae and genus mobilivirus. Measles infection presents with symptoms that include fever, coryza, cough, conjunctivitis and maculopapular rashes (Koplik's spots). Measles causes temporary suppression of the immune system, giving rise to secondary infections in patients. A person infected with measles will recover within three weeks if the infection is not complicated. Complications that can arise from measles infection include Subacute sclerosing panencephalitis (SSPE) , a disease which affects the central nervous system. An infected person that recovers from measles usually becomes immune to the disease for life.
The World Health Organization has adopted measles eradication goals, particularly after the successful eradication of naturally- occurring smallpox in 1977. This goal will most likely be achieved once the major challenges causing difficulty is overcome. These include the lack of effective vaccine delivery methods to rural areas and the inadequate number of trained medical personnel to efficiently administer these vaccines, as well as poor surveillance and undereporting of cases.
This review aims at appraising the current …show more content…
The causative agent is known as measles virus (MeV) . MeV is a negative-sense, non-segmented, single-stranded enveloped RNA virus from the family Paramyxoviridae and genus Morbillivirus. It measures approximately 15.9 kb (5,6,7). The MeV particle is pleomorphic and its nucleocapsid has helical symmetry. The envelope contains two virally coded glycoproteins: The F (fusion) protein and hemagglutinin (H), which is an attachment protein (a glycoprotein that binds to receptors on the host cell). Together, these two mediate viral entry. The nucleoprotein (N) encapsidates the viral genome and is the most abundant viral protein in the virion and in infected cells