Leishmaniasis is a parasitic disease spread by the bite of infected sand flies. There are several different forms of leishmaniasis. The most common are cutaneous and visceral. The cutaneous type causes skin sores. The visceral type affects internal organs such as the spleen, liver, and bone marrow. People with this form usually have fever, weight loss, and an enlarged spleen and liver.Leishmaniasis is found in parts of about 88 countries. Most of these countries are in the tropics and subtropics. Example of parasites of old world leishamniasis are L.Donovani,L.Infantum,L. Tropica,L. major and L. Aethiopica. They are transmitted to man by the bite of female sand flies Phlebotomus. Example of parasite of new world leishmaiasis are L. peruviana,L.chagasi,L.mexicana and L. braziliensis. They are carried by sand flies of the genus Lutzomyia and Psychodopygus. Pass life cycle in two hosts;Invertibrates- sand flies and vertibrates – mammals. In vertibrates the parasite resides within the phagolysosomal system of mononuclear phagocytic cells, mainly macrophages.In the invertibrates host the parasite are extracellular. Development occurs in the gut and transmission mouth during blood feeding.
Trypanosoma is a genus of kinetoplastids (class Kinetoplastida), a monophyletic group of unicellular parasitic flagellate protozoa It's also the cause of a severe (and often fatal) disease in humans called Trypanosomiasis. Trypanosomiasis, also known as sleeping sickness is a parasitic diseasetransmitted by the bite of the 'Glossina' insect, commonly known as the tsetse fly. The disease affects mostly poor populations living in remote rural areas of Africa. Untreated, it is usually fatal. Travelers also risk