Unknown Lab Report
Unknown Lab Report
Unknown Organism #6
Ann Le (Phuoc)
May 6, 2010
Dr. Carrington
Microbiology Lab- MW 12:50
Le 1
I. Introduction
My unknown organism #6 is Morganella morganii, which is a gram-negative bacillus rods commonly found in the environment and also in the intestinal tracts of humans, mammals, and reptiles as a normal flora. (3, 5) This bacterium Morganella morganii, was first discovered in the 1906 by a British bacteriologist named H. de R. Morgan. (2) Despite its wide distribution, it is an uncommon cause of community-acquired infection and is most often encountered inpostoperative and other nosocomial settings. (2, 3) Morganella morganii infections respond well to appropriate antibiotic therapy; however, its natural resistance to many beta-lactam antibiotics may lead to delays in proper treatment Morganella morganii was previously classified under the genus Proteus as Proteus morganii. (7)
The genus Morganella currently consists of only one species, belongs to the tribe Proteeae of the family Enterobaci Morganella morganii, with two subspecies, morganii and sibonii. (6) In the late 1930s, Morganella morganii was identified as a cause of urinary tract infections and also sepsis, pneumonia, wound infections, musculoskeletal infections, CNS infections, pericarditis, chorioamnionitis, endophthalmitis, empyema, and spontaneous bacterial peritonitis. (7, 8) Anecdotal reports of nosocomial infections
Le 2 began to appear in the literature in the 1950s and 1960s. (3) Tucci and Isenberg reported a cluster epidemic of Morganella morganii infections occurring over a 3-month period at a general hospital in 1977and of these infections, 61% were wound infections and 39% were urinary tract infections. (2, 4) The most common source of bacteraemia was postoperative wound infection, and most infections occurred in patients who had received recent therapy with a beta-lactam antibiotic. (6) Other important epidemiological risk factors in these
Unknown Organism #6
Ann Le (Phuoc)
May 6, 2010
Dr. Carrington
Microbiology Lab- MW 12:50
Le 1
I. Introduction
My unknown organism #6 is Morganella morganii, which is a gram-negative bacillus rods commonly found in the environment and also in the intestinal tracts of humans, mammals, and reptiles as a normal flora. (3, 5) This bacterium Morganella morganii, was first discovered in the 1906 by a British bacteriologist named H. de R. Morgan. (2) Despite its wide distribution, it is an uncommon cause of community-acquired infection and is most often encountered inpostoperative and other nosocomial settings. (2, 3) Morganella morganii infections respond well to appropriate antibiotic therapy; however, its natural resistance to many beta-lactam antibiotics may lead to delays in proper treatment Morganella morganii was previously classified under the genus Proteus as Proteus morganii. (7)
The genus Morganella currently consists of only one species, belongs to the tribe Proteeae of the family Enterobaci Morganella morganii, with two subspecies, morganii and sibonii. (6) In the late 1930s, Morganella morganii was identified as a cause of urinary tract infections and also sepsis, pneumonia, wound infections, musculoskeletal infections, CNS infections, pericarditis, chorioamnionitis, endophthalmitis, empyema, and spontaneous bacterial peritonitis. (7, 8) Anecdotal reports of nosocomial infections
Le 2 began to appear in the literature in the 1950s and 1960s. (3) Tucci and Isenberg reported a cluster epidemic of Morganella morganii infections occurring over a 3-month period at a general hospital in 1977and of these infections, 61% were wound infections and 39% were urinary tract infections. (2, 4) The most common source of bacteraemia was postoperative wound infection, and most infections occurred in patients who had received recent therapy with a beta-lactam antibiotic. (6) Other important epidemiological risk factors in these
References: 1. Carrington, Elizabeth, Ph.D. Microbiology Laboratory Manual. Second Edition. Dubuque: Kendall Hunt Publishing Company, 2006, 2009. 2. E Almaz, et al. "First case of CAPD-related peritonitis caused by Morganella morganii." Peritoneal Dialysis International: Journal Of The International Society For Peritoneal Dialysis 30.1 (2010): 119-121. MEDLINE. EBSCO. Web. 1 May 2011>. 3. Farmer, J. J., III, B. R. Davis, F. W. Hickman-Brenner, A. McWhorter, G. P. Huntley-Carter, M. A. Asbury, C. Riddle, H. G. Wathen-Grady, C. Elias, G. R. Fanning, A. G. Steigerwalt, C. M. O 'Hara, G. K. Morris, P. B. Smith, and D. J. Brenner. 1985. Biochemical identification of new species and biogroups of Enterobacteriaceae isolated from clinical specimens. J. Clin. Microbiol. 21:46-76 4. Fulton, M. 1943. The identity of Bacterium columbensis Castellani. J. Bacteriol. 46:79-82 5. Hu, L. T., E. B. Nicholson, B. D. Jones, M. J. Lynch, and H. L. Mobley. "Journal of Bacteriology." Morganella Morganii Urease: Purification, Characterization, and Isolation of Gene Sequences 176.6 (1990): 3073-080. Department of Medicine, University of Maryland School of Medicine. Web. 1 May 2011. <http://Journals.ASM.org>. Le 12 6. Katz, L. M., R. J. Lewis, and D. G. Borenstein. 1987. Successful joint arthroplasty following Proteus morganii (Morganella morganii) septic arthritis: a four-year study. Arth. Rheum. 30:583-585. 7. McDermott, Carolyn, and Joseph M. Mylotte. "Morganella Morganii: Epidemiology of Bacteremic Disease." Infection Control 5.3 (1984): 131+. The University of Chicago Press on Behalf of The Society for Healthcare Epidemiology of America. Web. 1 May 2011. <http://www.jstor.org/stable/30142630>. 8. Winslow, C.-E. A., I. J. Kligler, and W. Rothberg. 1919. Studies on the classification of the colon-typhoid group of bacteria with special reference to their fermentative reactions. J. Bacteriol. 4:429-503