What Is Nucleophilic Multistep Synthesis

In the reaction mechanism, the alpha hydroxyketone’s hydroxylic group attacks the positively charged nitrogen from nitric acid attaching it to the molecule. The nitrogen’s electrons are then kicked off on to the oxygen bearing a positive charge, creating water. This process formed an organic nitrate. Next, water is used to abstract hydrogen from the positively charged oxygen, forming hydronium. A carbonyl is formed as well as nitrogen dioxide gas. Simultaneously the oxygen separates itself from nitrogen dioxide by pushing its electrons onto the positively charged nitrogen. This forms benzil and nitrogen dioxide gas. The next series of reactions will occur using the benzil product formed and potassium hydroxide. Next, there is a nucleophilic
It is so crucial because it allows for the understanding of how molecules interact in order to create new products. Generally speaking, multistep synthesis could be useful in a practical application such as pharmaceutical chemistry. Synthesizing aspirin is a common example of a multistep synthesis reaction. Aspirin is typically taken as a painkiller or as a reducing-agent for fevers. In order to synthesize this product, the reactants salicylic acid and acetic anhydride (in excess) are used in the presence of a catalyst to create the product acetylsalicylic acid and acetic anhydride. Acetylsalicylic acid is the active pharmaceutical ingredient in aspirin and the catalyst is not consumed in the reaction. A catalyst is only used to speed up the reaction. While aspirin is an over the counter drug, it is crucial that it is prepared correctly, if the wrong amount of a compound is put into the drug, the individual taking the drug could suffer from a range of side effects. These side effects could include bruising, dizziness, nausea, vomiting etc. (everydayhealth), however, these side effects can also occur even when the product is synthesized