The first step involves the nucleophilic acyl substitution reaction of acetic anhydride with aniline to form acetanilide. The reaction is initiated by the donation of the lone pair of electrons on the nitrogen atom on aniline to the electron deficient carbonyl carbon atom in acetic anhydride, which is followed by the carbon oxygen double bond breaking in the electron deficient carbon with the oxygen taking the pair of electrons and resulting in a negative charge being present on oxygen and results in the formation of a tetrahedral intermediate. The next step involves the deprotonation of the positively charged nitrogen, which is then followed by reformation of the oxygen-carbon double bond and the loss of the acetate
The first step involves the nucleophilic acyl substitution reaction of acetic anhydride with aniline to form acetanilide. The reaction is initiated by the donation of the lone pair of electrons on the nitrogen atom on aniline to the electron deficient carbonyl carbon atom in acetic anhydride, which is followed by the carbon oxygen double bond breaking in the electron deficient carbon with the oxygen taking the pair of electrons and resulting in a negative charge being present on oxygen and results in the formation of a tetrahedral intermediate. The next step involves the deprotonation of the positively charged nitrogen, which is then followed by reformation of the oxygen-carbon double bond and the loss of the acetate