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Why Does The Purkinje Initialize The Depolarization Of The

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Why Does The Purkinje Initialize The Depolarization Of The
The heart is the contractile organ that provides the bloodstream due to excitation-contraction coupling.
It has cells that initiate and propagate the excitement like nodal cells and the conductive tissue, as well as cells which answer to the excitement by a contraction like myocardial cells or cardiomyocytes.\\
The propagation of the excitation in the heart is also called the propagation of the depolarization wave that is initiated in the sinus node.
This spread is not performed continuously between the atrium and ventricle but by the specialized conduction system, beginning with the his bundle and which finishes with the purkinje network, that allows the wave of depolarization to cross the nonconductive wall wich separates the atrium and the
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In \cite{bordas}, based on the bidomain model, the author used the assumption that the conduction system and the myocardium are coupled only by the extracellular potential. His work is nearer to physiology : the activation of the ventricle follows the activation of th purkinje with delay of 5 ms, then the PVJ is represented as a resistive barrier connecting the intracellular space of a Purkinje fiber to
The same model used in \cite{vigmond}, the propagation of the action potential of purkinje cell to the ventricle passes through PVJ, and is characterized by delayed excitation, the delay has been alternately attributed to changes in the conductive geometry and the connection is made at the level of extracellular potential. \\
We note that this type of coupling does not take into account the scale effect between the outgoing current 1D and th 3D current in the muscle.\\
On the other side, the author in \cite{azzouzi} used a new approach, it's based on using the monodomain model of both in the myocarde and th purkinje

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