Abstract
Cyclobenzaprine is a skeletal muscle relaxant. It is marketed as Flexeril and also as Fexmid. This experiment will observe the effects that cyclobenzaprine have on the body as well as the inflammation area of the body. The inflammation area of the individual who tested the drug was the lumber or lower back region of the body. The observations were conducted over a period of three days.
Introduction
Cyclobenzaprine is a skeletal muscle relaxant. It is marketed as Flexeril (10 mg tablets) and also as Fexmid (7.5 mg tablet). Both the 5 and 10 milligram tablets are available generically. Fexmid is not available generically and few pharmacies carry it for this reason. Once-a-day extended release formulation, Amrix, has been approved by the American FDA in 2007 and is available in 15 and 30 mg capsules.
Cyclobenzaprine and another similar muscle relaxant trazadone are structurally related to the first-generation tricyclic antidepressants such as imipramine. It therefore should not be used within 14 days of cessation of therapy with monoamine oxidase inhibitors (MAOIs).
The exact mechanism of action for cyclobenzaprine is unknown. Current research appears to indicate that cyclobenzaprine acts on the locus coeruleus where it results in increased norepinephrine release, potentially through the gamma fibers which innervate and inhibit the alpha motor neurons in the ventral horn of the spinal cord. Decreased firing of the alpha motor neuron results.
Cyclobenzaprine: IUPAC name: 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)- N,N-dimethyl-1-propanamine
Cyclobenzaprine is typically prescribed to relieve pain and muscle spasms. Typically, muscle spasms occur in an injury to stabilize the affected body part and prevent further damage. The spasm of the muscles can increase the pain level. It is believed that by decreasing muscular spasm, pain is diminished. A common application would be that of a whiplash injury in a