FEVER
BY: CATHERINE E. JOAQUIN
REPORT CONTENT
INTRODUCTION
SIGNS AND SYMPTOMS
PATHOGENS AND VIRULENCE FACTORS
PATHOGENESIS/TRANSMISSION
EPIDEMIOLOGY
DIAGNOSIS, TREATMENT AND PREVENTION
INTRODUCTION
What are Food & Waterborne
Diseases?
Diseases
that are supported, carried or transmitted by food & water.
Examples
are: Cholera, Hepatitis A,
Amoebic Dysentery, & Typhoid Fever
INTRODUCTION
What is a Typhoid Fever?
It
is an acute bacterial infection characterized by fever, headache and abdominal discomfort.
Also
known as ENTERIC FEVER
PATHOGENS & VIRULENCE FACTORS
What causes Typhoid Fever?
Typhoid
Fever is caused by the bacterium Salmonella typhi from the family Enterobacteriacea.
Salmonella
typhi is a gram-negative bacteria that is motile due to its peritrichous flagella
The
bacteria grows best at 37°C.
Color pink therefore Gramnegative
With peritrichous flagella PATHOGENS & VIRULENCE FACTORS
can also be caused by Salmonella paratyphi, a related bacterium that usually causes a less severe illness known as Paratyphoid Fever.
It
PATHOGENESIS
How does the bacteria cause disease? Ingestion of contaminated food or water Salmonella bacteria penetrate the epithelial wall of the small intestine Phagocytosed by macrophages
PATHOGENESIS
How does the bacteria cause disease? S. typhi then alters its structure to resist destruction and allow them to exist within the macrophage Spread via the lymphatics while inside the macrophages
Travels to the reticulo endothelial system and then to the different organs throughout the body
PATHOGENESIS
How does the bacteria cause disease? Goes back to the bloodstream accompanied with development of symptoms
Salmonella bacteria may be passed out through the stool
Cycle continues SIGNS AND