an ester either with the hydroxyl or with the acid. In the presence of acetic anhydride‚ acetylsalicylic acid (aspirin or ASA) is formed. Correspondingly‚ an excess of methanol will form methyl salicylate‚ which is also an analgesic. In this experiment‚ we shall use the former reaction to prepare aspirin. Salicylic acid will not react significantly with acetic acid to produce aspirin. Acetic acid anhydride‚ however‚ is more reactive than acetic acid because the acetoxy group (-O2CCH3)
Free Aspirin Acetic acid Carboxylic acid
Starting Material Appearance: white powder Molar Mass: 138.12 g/mol Melting Point: 1590C Boiling Point: 2110C Density: 1.44 g/cm3 Mildly irritating (pulmonary irritants). Harmful by inhalation‚ ingestion and through skin absorption. Acetic Anhydride Starting‚ Material‚ serves also as the solvent colorless liquid with a smell of acetic acid Molar Mass: 102.09 g/mol Melting Point: -73.1 0C Boiling Point: 139.8 0C Density: 1.082g/cm3 Corrosive Flammable and Lachrymator which makes eyes
Free Aspirin Acetic acid Acetic anhydride
Experiment No. 1: MELTING POINT AND BOILING POINTS OF ORGANIC COMPOUNDS ABSTRACT The properties of organic compounds depend on their chemical structures. Intermolecular forces of attraction affect physical properties such as melting and boiling point. Through the Thomas Hoover apparatus‚ the melting point of 8 test compounds was determined. Salicylic acid exhibited the highest melting point while naphthalene‚ the lowest. The stronger the intermolecular forces of attraction‚ the higher the melting
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CHEM 3152-003 Experiment 2: Fractional Distillation and Gas Chromatography Introduction: The purpose of this experiment was to separate a mixture of ethyl acetate (EtOAc) and toluene by using the method of fractional distillation and to analyze the fractions using gas chromatography (GC). ethyl acetate toluene Distillation is a method known as separating or purifying a liquid or mixture by vaporization and condensation. In a simple distillation‚ the liquids being separated boil below 150 0C
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University of Santo Tomas Abstract Recrystallization is a technique used to purify organic solids. This method involves dissolving of a solute in a solvent and inciting the solute to produce a precipitate from a solution. In this experiment‚ acetic anhydride was added to the mixture of 2mL aniline and 20mL of distilled water. The mixture was cooled in an ice bath and filtered through filter paper resulting to the crude acetanilide. The pure acetanilide was then produced by the filtered solution of crude
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of the aspirin sample‚ which will in turn indicate the purity of the sample. The last is conducting a colorimetric analysis on the aspirin sample. The educational goals of this lab are to find the structural formulas for salicylic acid‚ acetic anhydride‚ and aspirin and to use these structural formulas to construct a reaction equation by describing the synthesis of aspirin. In addition‚ you have to be able to use your percent purity calculations to determine the percent yield of your synthesis of
Free Aspirin Acetic acid Acetic anhydride
color Br2/CH2Cl 2 the solution turned orange. Orange color held. Alkene Alkene used was pentene. Originally clear liquid. After addition‚ solution turned yellowish at first but then turned clear after a few minutes of sitting. Alkyne Alkyne used was toluene. Originally clear liquid. After addition‚ solution turned orange. Orange maintained longer than alkene but eventually turned clear. Unknown Originally clear liquid. After addition of unknown‚ turned orange but eventually faded to clear color after
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Materials Chemicals Equipment Safety Containers Measuring Devices Other Equipment Procedure Synthesis of Aspirin Crystalizing the Aspirin Recrystallizing the Crude Aspirin Finding the Melting Point Range Safety Precautions Acetic Anhydride Sulphuric and Salicylic Acid Heating Observations Mass of Aspirin Synthesized Melting Point Calculations Percentage Yield Maximum Yield Crude Product Final Product Melting Range Percentage Error Crude Product Final Product Conclusion
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DISTILLATION- SEPARATION OF A MIXTURE Ronald Ogbu‚ Alex 27th Aug. 2013 Purpose: To separate mixture of acetone and toluene using simple‚ packed and unpacked distillation columns. Results and Discussion: There were three distillation setups: simple‚ unpacked and pack fractional. All three procedures had different distillation apparatus but the unknown mixture was the same for all. The unknown liquid in a 50 ml round bottom flask was heated in a heating mantle such that a
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hydrocarbons using properties and reactions. b) Study substitution and addition reactions. Equipments test tube rack (1) test tube holder (2) 100 mL beaker medium test tube (6) Materials cyclohexene toluene n-hexane conc. H2SO4 Br2/CCl4 or Br2/CH2Cl2 0.50 % KMnO4 10% NaOH 10% Na2CO3 unknowns hydrocarbons Discussion Hydrocarbons‚ compounds which contain only carbon and hydrogen‚ can be classified into several types‚ depending
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