Acetylsalicylic Acid (Aspirin) Synthesis Telow‚ AJV Sumicad‚ CJ‚ Tavanlar‚ EMMT‚ Chem 40.1‚ Institute of Chemistry‚ University of the Philippines Los Baños I. Introduction Organic synthesis is the process where a desired organic compound is constructed or prepared from commercially available materials. The objective of organic synthesis is to design the simplest synthetic routes to a molecule. Aspirin‚ also known as acetylsalicylic acid is as salicylate drug often used as analgesic
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INTRODUCTION 3 2.1 The background information of Aspirin 3 2.11 History 3 2.12 chemical structures 4 2.2 The background information of Acetaminophen 5 2.21 History 5 2.22 Chemical Structures 6 3.0 BODY 6 3.1 Synthesis 6 3.11 Synthesis of Aspirin 6 3.12 Synthesis of Acetaminophen 7 3.2 Mechanism of Action in Human Body 9 3.2.1 Pain as a warning system 9 3.2.2 Aspirin 9 3.2.3 Acetaminophen 10 3.3 Side effects 10 3.3.1 Side effects of Aspirin 10 3.3.2 Side effects of Acetaminophen 11 4
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contains 85g of NaNO3 in 100g of H2O. So‚ in 200g of water‚ mass of NaNO3 needed to make a saturated solution: = 2 x 85 = 170g 80 g of NaNO3 has already been added to 200g H2O So the extra amount of NaNO3 needed: = 170 – 80 = 90g Crystallisation Crystallisation: when a solute turns to form crystals Sugar becomes less soluble as it cools in honey o Sugar no longer stays dissolved and comes out of the solution as crystals Worked example What happens if a solution containing 50g of potassium
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ASSESSMENT OF PRIMARY HEMOSTASIS 1.BLEEDING TIME Bleeding time is used to measure the duration of bleeding after a measured skin incision. Bleeding time may be measured by one of three methods: template‚ Ivy‚ or Duke. The template method is the most commonly used and the most accurate because the incision size is standardized. Bleeding time depends on the elasticity of the blood vessel wall and on the number and functional capacity of platelets. Although this test is usually performed on
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Name Period Date The Synthesis of Aspirin Background Pharmaceutical research labs perform chemical reactions between organic molecules that contain mostly carbon. Since the atoms in organic molecules tend to be nonmetals‚ then the bonds that hold them together are covalent bonds. Only a few elements on the periodic table are nonmetals: C‚ N‚ O‚ S‚ Cl‚ and F. This small number of elements can be bonded together in different quantities‚ bonding types (single‚ double‚ triple bonds)‚ and structural
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sakshieducation.com b) Non - narcotic analgesics: These drugs are analgesics but they have no addictive properties. Their analgesic use is limited to mild aches and pains like backache and headache. Ex: Aspirin‚ Ibuprofen etc. Aspirin: Chemically aspirin is ortho acetyl salicylic acid. Preparation: Acetylation of salicylic acid with acetic
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Anhydride Figure 11.3. The balanced chemical reaction of the formation of aspirin. Because the reaction is slow in pure acetic anhydride‚ the catalyst‚ commonly strong acids like phosphoric acid was used for the reaction. According to Le Chatelier’s principle‚ the presence of excess acetic anhydride forces the equilibrium towards the desired product‚ which in this case is the aspirin. In addition to this‚ the catalysts were also used to ensure that side reactions‚ which may
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CHE3049W – EFC Report Synopsis This report provides a detailed investigation into the operation of the Eutectic Freeze Crystallisation (EFC) process in order to determine its effectiveness as a separation technique for purification of waste water streams. The objective of is to evaluate the ability of the EFC process in reducing the volume of a 5 wt% CuSO4 aqueous waste water stream significantly while simultaneously producing potable (drinking) water. In order to evaluate this effectiveness
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being given our own Salicylic acid (SA) prepared for us instead of having to used wintergreen to make it and recrystallize it. In addition‚ we skipped the qualitative test of our purity for SA and Aspirin (ASA). The first part of this experiment is the preparation of ASA from SA were‚ we prepared our aspirin from the collected salicylic acid. A screw-capped vial was weighed empty to 29.7416 grams and filled with SA. The mass recorded of SA was 1.3995 grams of SA and it was weighed and transferred to
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the test tube by displacing the water. After that‚ bring out the test tube and ignite it. For Preparation of Iodoform‚ a Halogen Derivative (or Alkyl Halide)‚ first place two milliliter of ethyl in a small beaker and add few crystals of iodine and stir to dissolve. Then‚ add 10% sodium hydroxide solution and stir it until its goes from brown to yellow. Record the observation on the data sheet. For preparation of ethyl acetate‚ first place 3 mL of glacial acetic acid in a test tube and describe the odor
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