4 Androstenediol Case Study
4-androstenediol:
Like androstenedione, 4-androstenediol is an efficient precursor to testosterone. In fact it appears comparatively much more so, as it utilizes a more active enzyme in its biotransformation to testosterone. Rough estimates are the 2 to 3 times more prohormone is needed for the same testosterone elevation with the preceding product. 4-androstenediol also avoids the direct path of metabolism to estrogen we see with androstenedione, as its diol structure resists interaction with the enzyme responsible for this conversion. Clearly this represents a further improvement, making this compound the most effective choice in this category.
5-androstenediol:
5-androstenediol is technically a testosterone precursor, however it has a …show more content…
It is therefore slightly more potent in comparison to 19-norandrostenedione, however both of these two nandrolone precursors are considered solidly effective anabolics. Only those extremely sensitive to estrogen or using unusually high amounts will likely ever notice a difference in estrogen conversion rates, although technically this prohormone would be more suitable in this regard as it avoids any possible direct path of conversion (the same trait noted with 4-androstenediol). Otherwise these two precursors are really interchangeable. Combining these two prohormones (as in DermaGAIN™) actually seems to be the most advantageous method of taking nandrolone precursors, as this utilizes two distinct paths of metabolism for the optimal buildup of active steroid in the blood …show more content…
DHT is typically thought of as a side effect hormone, however this is more a product of misunderstanding than fact. In the human body DHT is much more active than testosterone, and is produced locally in tissues sensitive to androgen action such as the prostate, skin, scalp and certain areas of the central nervous system. It is for this reason that its presence is usually associated with side effects, however it activates the same cellular receptor that testosterone does. The applications for a DHT prohormone are actually quite numerous, as it represents the only truly non-aromatizable (will not convert to estrogen) prohormone available. The non-aromatizing androgen is an important class of steroid to the athlete/bodybuilder (Masteron (2-methylDHT), Parabolan (trenbolone), Proviron (1-methylDHT) and Halotestin (fluoxymesterone) are such compounds), as they are excellent for shifting the androgen/estrogen ratio and promoting increased fat loss, muscle hardness and vascularity. Similar to these mentioned items, DHT is a very potent androgenic steroid. The strong effect DHT has on the central nervous system also helps to greatly support the buildup of strength, and its high affinity for serum binding proteins allows it to competitively force more testosterone into a free state when taken with such a steroid or prohormone. DHT is also an efficient anti-aromatase (inhibitor of
Like androstenedione, 4-androstenediol is an efficient precursor to testosterone. In fact it appears comparatively much more so, as it utilizes a more active enzyme in its biotransformation to testosterone. Rough estimates are the 2 to 3 times more prohormone is needed for the same testosterone elevation with the preceding product. 4-androstenediol also avoids the direct path of metabolism to estrogen we see with androstenedione, as its diol structure resists interaction with the enzyme responsible for this conversion. Clearly this represents a further improvement, making this compound the most effective choice in this category.
5-androstenediol:
5-androstenediol is technically a testosterone precursor, however it has a …show more content…
It is therefore slightly more potent in comparison to 19-norandrostenedione, however both of these two nandrolone precursors are considered solidly effective anabolics. Only those extremely sensitive to estrogen or using unusually high amounts will likely ever notice a difference in estrogen conversion rates, although technically this prohormone would be more suitable in this regard as it avoids any possible direct path of conversion (the same trait noted with 4-androstenediol). Otherwise these two precursors are really interchangeable. Combining these two prohormones (as in DermaGAIN™) actually seems to be the most advantageous method of taking nandrolone precursors, as this utilizes two distinct paths of metabolism for the optimal buildup of active steroid in the blood …show more content…
DHT is typically thought of as a side effect hormone, however this is more a product of misunderstanding than fact. In the human body DHT is much more active than testosterone, and is produced locally in tissues sensitive to androgen action such as the prostate, skin, scalp and certain areas of the central nervous system. It is for this reason that its presence is usually associated with side effects, however it activates the same cellular receptor that testosterone does. The applications for a DHT prohormone are actually quite numerous, as it represents the only truly non-aromatizable (will not convert to estrogen) prohormone available. The non-aromatizing androgen is an important class of steroid to the athlete/bodybuilder (Masteron (2-methylDHT), Parabolan (trenbolone), Proviron (1-methylDHT) and Halotestin (fluoxymesterone) are such compounds), as they are excellent for shifting the androgen/estrogen ratio and promoting increased fat loss, muscle hardness and vascularity. Similar to these mentioned items, DHT is a very potent androgenic steroid. The strong effect DHT has on the central nervous system also helps to greatly support the buildup of strength, and its high affinity for serum binding proteins allows it to competitively force more testosterone into a free state when taken with such a steroid or prohormone. DHT is also an efficient anti-aromatase (inhibitor of