Anemia is usually defined as a decrease in amount of red blood cells (RBCs) or the amount of hemoglobin in the blood. It can also be defined as a lowered ability of the blood to carry oxygen. When anemia comes on slowly the symptoms are often vague and may include: feeling tired, weakness, shortness of breath or a poor ability to exercise. Anemia that comes on quickly often has greater symptoms which may include: confusion, feeling like one is going to pass out, and an increased desire to drink fluids. There needs to be significant anemia before a person becomes noticeably pale. There may be additional symptoms depending on the underlying cause.
Certain groups of individuals, such as pregnant people, benefit from the use of iron pills for prevention. Dietary supplementation, without determining the specific cause, is not recommended. The use of blood transfusions is typically based on a persons signs and symptoms. In those without symptoms they are not recommended unless hemoglobin levels are less than 60 to 80 g/L (6 to 8 g/dL). These recommendations may also apply to some people with acute bleeding. Erythropoiesis-stimulating medications are only recommended in those with severe anemia.
Anemia is the most common disorder of the blood with it affecting about a quarter of people globally. Iron-deficiency anemia affects nearly 1 billion. It is more common in females than males among children, during pregnancy and in the elderly. Anemia increases costs of medical care and lowers a person's productivity through a decreased ability to work.
Epidemiology
A moderate degree of iron-deficiency anemia affected approximately 610 million people worldwide or 8.8% of the population. It is slightly more common in female (9.9%) than males (7.8%). Mild iron deficiency anemia affects another 375 million.
Signs And Symptoms
Anemia goes undetected in many people, and symptoms can be minor or vague. The signs and symptoms can be related to the underlying cause or