APPLICATION OF MONOCLONAL ANTIBODIES
Biweekly Assignment Three
Applications of Monoclonal Antibodies
BTEC 221
Prepared by: Sandipkumar R. Italiya (300782816)
Submitted to: Dr. Charanjit Bambra
Monoclonal antibody technology becomes very useful in every day operations in different fields, involving mainly in the medical field, furthermore very much contribution in academic as well as in business part among the others. Main applications of monoclonal antibodies are mentioned below, even now holding limitlessness of the benefits of monoclonal antibodies.
In Cancer Treatment
A monoclonal antibody is a research facility created particle that is precisely designed to join to particular defects in tumour cells. Monoclonal antibodies emulate the antibodies your body commonly creates as a major aspect of your immune system 's reaction to germs, immunizations and different invaders.
The immune system assaults foreign intruders in your body, however it doesn 't generally perceive recognize cancer cells as enemies. A monoclonal antibody can be regulated to connect to specific parts of a growth cell. Along these lines, the immune response denote the cancer cell and makes it simpler for the immune system to discover.
The monoclonal antibody medicine rituximab (Rituxan) joins to a particular protein (Cd20) discovered just on B cells, one kind of white platelet. Certain sorts of lymphomas emerge from these same B cells. At the point when rituximab connects to this protein on the B cells, it makes the cells more noticeable to the insusceptible framework, which can then assault. Rituximab brings down the quantity of B cells, including stonge B cells, however body delivers new solid B cells to supplant these. The cancerous B cells are less inclined to repeat.
Growth cells depend on veins to convey them the oxygen and supplements they have to develop. To attract veins, tumour cells convey development signals.Monoclonal antibodies that piece these development signs may help keep a tumor from creating a blood
Applications of Monoclonal Antibodies
BTEC 221
Prepared by: Sandipkumar R. Italiya (300782816)
Submitted to: Dr. Charanjit Bambra
Monoclonal antibody technology becomes very useful in every day operations in different fields, involving mainly in the medical field, furthermore very much contribution in academic as well as in business part among the others. Main applications of monoclonal antibodies are mentioned below, even now holding limitlessness of the benefits of monoclonal antibodies.
In Cancer Treatment
A monoclonal antibody is a research facility created particle that is precisely designed to join to particular defects in tumour cells. Monoclonal antibodies emulate the antibodies your body commonly creates as a major aspect of your immune system 's reaction to germs, immunizations and different invaders.
The immune system assaults foreign intruders in your body, however it doesn 't generally perceive recognize cancer cells as enemies. A monoclonal antibody can be regulated to connect to specific parts of a growth cell. Along these lines, the immune response denote the cancer cell and makes it simpler for the immune system to discover.
The monoclonal antibody medicine rituximab (Rituxan) joins to a particular protein (Cd20) discovered just on B cells, one kind of white platelet. Certain sorts of lymphomas emerge from these same B cells. At the point when rituximab connects to this protein on the B cells, it makes the cells more noticeable to the insusceptible framework, which can then assault. Rituximab brings down the quantity of B cells, including stonge B cells, however body delivers new solid B cells to supplant these. The cancerous B cells are less inclined to repeat.
Growth cells depend on veins to convey them the oxygen and supplements they have to develop. To attract veins, tumour cells convey development signals.Monoclonal antibodies that piece these development signs may help keep a tumor from creating a blood
References: Monoclonal antibody drugs for cancer: How they work; By: Mayo Clinic; http://www.mayoclinic.org/diseases-conditions/cancer/in-depth/monoclonal-antibody/art-20047808 Monoclonal antibodies show promise as effective HIV therapy; Beth Israel Deaconess Medical Center; http://www.sciencedaily.com/releases/2013/10/131030142412.htm Antibodies in Medical Treatment and Diagnosis; By: Reven, Johnson, Mason, Losos and Singer 9th edition by McGraw Hill; https://www.inkling.com/read/biology-peter-raven-9th/chapter-52/antibodies-in-medical-treatment Some properties and applications of monoclonal antibodies; By: Paul A. W. Edwards; http://www.biochemj.org/bj/200/0001/2000001.pdf