To begin with, one similarity was that all of the colonies were in some sort of industry where they gained profit for themselves or for the King and they were able to partake in a global trade. Also, the colonists in the colonies believed themselves to be racially, culturally, and spiritually superior to the slaves and the Indians. The temperature climates in the regions were also similar. Most of the colonies had easy access to the Atlantic Ocean both along their coasts and by using river systems that were navigable for miles inland.
In addition to that, one difference was that they all ran their democratic government differently. The New England Colonies were a theocracy, which meant that the church controlled the government. The Middle Colonies had their government and church separated. The Southern Colonies were an Oligarchy, which meant that wealthy plantation owners controlled the government since they could pay for their expenses. Also, the first colonists to step on New England were Separatist Puritans (Pilgrims), the first people to step on the Middle Colonies were the Dutch where they settled at the mouth of the Hudson River, and the first colonists to step on the Southern Colonies were the English where they settled in Jamestown, Virginia.
In conclusion, the thirteen colonies that were New England, Middle, and Southern had their similarities and differences. The founders of each region had a purpose or goal that they wanted to achieve so they each founded land that would allow settlers to be happy with their choosing of where to settle between