Preview

Comparing Dna Sequences to Understand Evolutionary Relationships with Blast

Better Essays
Open Document
Open Document
1682 Words
Grammar
Grammar
Plagiarism
Plagiarism
Writing
Writing
Score
Score
Comparing Dna Sequences to Understand Evolutionary Relationships with Blast
Name: Rimsha Ahmed
John F Kennedy HS
Dr. Fisher
Date: 1-14-13
Block: 3

I. Comparing DNA Sequences to Understand Evolutionary Relationships with BLAST:

III. INTRODUCTION:
NULL HYPOTHEISIS: Mental disorders are not present in animals.
HYPOTHESIS:
As much as life has evolved, the relationship between animals and humans has remained very close to each other. If animals are, evolutionally, and genetically similar to humans; can they develop the same diseases we have today? Humans today have mental disorders left and right: OCD(obsessive compulsive disorder), autism, ADD (attention deficient disorder), bipolar disorder, depression, insomnia, anxiety. If all these diseases occur in the minds of humans, can they occur in the minds of animals also? Dogs share approximately 75% of their DNA with humans; can it occur in them too?
A lacking in the protein called SAPAP3 is believed to be the cause of OCD-related symptoms in mice. If the protein SAPAP3 is found in other organisms, can they be susceptible to mental disorders similar to OCD? If the protein named SAPAP3 is found in dogs, coyotes, wolves, foxes (taxid:9608) at more than 75% identical, then these animals are vulnerable to mental disorders similar to OCD.

VI. RESULTS: QUANTITATIVE:

These are our top 5 results. The first one is nearly identical to the gene, while the bottom four are barely half similar.

The most similar protein was found in Canis lupis familiaris. It is 96% identical and 97% similar. The E value is 0.0.

The second most familiar protein was also found in Canis lupis familiaris. This genome is significantly less similar. It is 47% identical, 57% similar, and has an E Value of 0.0.

QUALITATIVE: The first result has an almost entirely identical genome as the one found to cause OCD- like symptoms in rats. This signifies, theoretically, that if there were to be an alteration or lacking in the genome in Canis lupis familiaris, the OCD-like symptoms found in

You May Also Find These Documents Helpful

  • Satisfactory Essays

    Hsc2 Unit 1 Assignment

    • 402 Words
    • 2 Pages

    i) The enzyme that would be used to cut the vector would be SalI along with adding the CIP. The main reason that you would cut with the particular enzyme Sal I is because the beginning of the vector sequence there isn’t a stop codon, so but cutting it with Sal I than both the vector and the protein will be compatible. There however is going to be a function of the CIP. CIP is a very important aspect of the whole process because once the vector is opened; the CIP is going to…

    • 402 Words
    • 2 Pages
    Satisfactory Essays
  • Satisfactory Essays

    p.19 from l.20. About the method to determine the number of duplicated genes. This strategy is conservative and will underestiamte the copy number. Please discuss on this possibility and the possible effect on the conclusion.…

    • 248 Words
    • 1 Page
    Satisfactory Essays
  • Satisfactory Essays

    DAT Study Guide

    • 734 Words
    • 3 Pages

    The nucleotide sequences for the same genes is aligned below. The red letters represent non-synonymous
replacements and the green letters are silent synonymous substitutions.…

    • 734 Words
    • 3 Pages
    Satisfactory Essays
  • Good Essays

    Living Primates Summary

    • 286 Words
    • 2 Pages

    Varki and Gagneux studied humans and chimpanzees to learn more about the gene’s lineage. Their…

    • 286 Words
    • 2 Pages
    Good Essays
  • Better Essays

    Ap Bio Lab Fruit Flies

    • 4015 Words
    • 17 Pages

    Fruit flies have made a huge contribution towards knowledge about genetics, but for most people, they are just annoying insects that are attracted to their fruit. Their scientific name is Drosophila melanogaster, and to scientists, they have been a key to understand many principles of heredity including sex linked inheritance, epistasis, multiple alleles, and gene mapping. Fruit flies were the first organisms to be used for genetic analysis in 1910 by Thomas Hunt Morgan, and ever since, they have been used for genetic experiments (Ashburner).…

    • 4015 Words
    • 17 Pages
    Better Essays
  • Satisfactory Essays

    bio lab on evolution

    • 776 Words
    • 3 Pages

    The 4 organisms that were looked at in the Gene 1 are bird, vertebrate, rodent and bony fish. From the Blast result the most similar gene sequence to the gene of the gene of interest is Gallus gallus collaged which is also a bird. They are the most similar because the Gallus has the highest max score out of all other genes and 100% for the ident and there is no difference in the e-value. The species is located at the bird’s branch. Its very similar due to the similarities in its ident value and its e-value. The second most similar gene sequence from my own results in the Gene table is Carvus Brachylagus, it has a max score of 6927, a 90% similarity in the ident and a same e-value as the gene of interest.…

    • 776 Words
    • 3 Pages
    Satisfactory Essays
  • Satisfactory Essays

    01.05 biology

    • 363 Words
    • 4 Pages

    -Differences and similarities in genetic codes could be used to determine how closely related different species are by comparing and contrasting the amino acids in their genetic code.…

    • 363 Words
    • 4 Pages
    Satisfactory Essays
  • Satisfactory Essays

    1.03 Biology

    • 339 Words
    • 2 Pages

    4.How might similarities and differences in genetic codes, or the proteins built as a result of these codes, be used to determine how closely related different species are?…

    • 339 Words
    • 2 Pages
    Satisfactory Essays
  • Good Essays

    The biological model compares abnormal behaviour with a disease. It assumes that all mental illnesses have a physiological cause related to the physical structure and brain. Doctors diagnose mental illness using well-established criteria. Psychiatrists also use diagnostic manuals for mental illness and compare symptoms with set classifications of illnesses. According to the biological model, mental illness is caused by one or more of the following factors; genetic inheritance, bio-chemistry and infection. The reason why genetic inheritance could be a possible cause for mental illness is due to the assumption that people have a genetic disposition to certain psychological disorders. For example, Kendler et al found relatives of schizophrenics were 18 times more likely to develop the illness than a matched control group. Bio-chemistry is also a factor that is considered as it is thought that chemical imbalances in the brain may be involved in certain mental illnesses. Neurotransmitters play an important part in behaviour. For example, an excess of dopamine has been detected in the brains of schizophrenics. This finding, however, has been assumed due to correlation which does not prove cause and effect. Infection is also thought to be a factor which could potentially cause mental illness as research suggests that some mental illnesses, such as schizophrenia, may be related to exposure to certain viruses in the womb. For example, Torrey found that the mothers of many people with schizophrenia had contracted a particular strain of influenza during pregnancy. It is supposed that the virus may have entered the unborn child’s brain and remained dormant there until puberty, when other hormones may have activated it.…

    • 652 Words
    • 3 Pages
    Good Essays
  • Powerful Essays

    Nt1310 Unit 4

    • 864 Words
    • 4 Pages

    36. Under the Biological Perspective: How has the depressed brain influenced the development of mood disorders?…

    • 864 Words
    • 4 Pages
    Powerful Essays
  • Good Essays

    The biological model of abnormalities is very different that conditioning by saying that mental abnormalities are very similar to illnesses such as the flu there are many different ways that illnesses can be developed biologically:…

    • 600 Words
    • 3 Pages
    Good Essays
  • Good Essays

    It is without question that DNA is the building blocks of any human being, recent studies have found that your genetic makup has a significant impact on how a person responds to stress, which can make certain people susceptible to mental illness, most notably depression. (Srijan Sen, 2011) It is believed that your DNA allows for a range of possible characteristics and tendencies that is then determined by your environment and daily activities. This last point of course leads to the heart of the controversy between genetic predisposition and environmental triggers, and which is more prominent. A study released by Livesley in 1993 is a perfect example of the attempt to link genetic predisposition strongly to mental illness and found that Narcissistic Personality Disorder had a 64% heritability rate. This study however was widely criticized as to having no consistency with its chosen participants and also failed to mention if any of the participants or their parents had a personality disorder. Due to these external variables, it was believed that the margin of error was too significant for the studies findings to hold any real merit in presenting a strong link between genetic predisposition and NPD in particular.…

    • 914 Words
    • 4 Pages
    Good Essays
  • Best Essays

    Obsessive-Compulsive disorder (OCD) was once considered to be a disease that was uncommon and even rare in the psychological field. Since more studies have been conducted on the disorder, the previous belief of rarity has been revoked and it is now considered to be grouped into the top ten disabling disease as characterized by the World Health Organization (WHO) (Zohar, J., M.D., & Hermesh, H., M.D. 2008). OCD is a common psychiatric disorder that involves “manifesting with obsessions and compulsions.” The obsessions are the “intrusive, recurrent, persistent, and unwanted thoughts,” while compulsions are the “repetitive behaviors or mental acts” (Bokor & Anderson, 2014). The orbitofrontal cortex, basal ganglia, and anterior cingulate gyrus are involved in the pathophysiology in the brain that contributes to the heterogeneity of OCD. A malfunction of the brain’s circuit cortico-striato-thalamo-cortical is suggested to be a primary cause of OCD, although genetics also play a part. There are numerous drugs that have been helpful in the treatment of OCD that allow the symptoms to subside “such as antipsychotics and dopaminergic agents” (Bokor & Anderson, 2014). Successful treatments of OCD include electroconvulsive therapy, psychotherapy, and pharmacotherapy, with the last resort being surgery (Bokor & Anderson, 2014).…

    • 2707 Words
    • 8 Pages
    Best Essays
  • Good Essays

    In this essay there will be comparisons and contrasts between the Generalized Anxiety Disorder and the Obsessive-Compulsive Disorder. A few comparisons are that both disorders can cause physical and mental symptoms such as restlessness, irritability, poor concentration, worrying, and can effect anyone. A few contrasts are that GAD is usually triggered by nothing specific, while OCD is triggered by one or a few specific things, and OCD can contain come as only obsessive, compulsive, or both. This essay will also talk about similarities and differences in diagnostics and whether these diagnostics are reasonable and/or easy-hard to determine.…

    • 591 Words
    • 3 Pages
    Good Essays
  • Satisfactory Essays

    Researchers studies DNA from human families affected by schizophrenia and found that those with Schizophrenia were more likely to have a defective version of a gene called PPP3CC; which is associated with calcineurin.…

    • 356 Words
    • 2 Pages
    Satisfactory Essays

Related Topics