D2L: What Is Receptor Complicated Endocytosis?
Module # 7
Chapter 12
Books cited: Becker’s world of the cell: J. Hardin, G. Bertoni, and L. Kleinsmith: 8th edition; pgs.343-345 & pgs. 356-358
Question #5 from D2L: What is receptor mediated endocytosis? Explain how it occurs.
Receptor meditated endocytosis is a way the cell uses endocytosis by absorbing coated vesicles by the means of clathrin and breaking down the absorbed materials so the cell can use it. Receptor mediated endocytosis begins by the binding of a protein to a receptor that is located on the plasma membrane. Next the receptors collect and cluster in coated pits, and then forms a vesicle.(pg. 343) Then adaptin binds to the receptor and clathrin then binds to adaptin, which then makes a shell that surrounds the outside of this vesicle. The protein dynamin causes it to detach from the plasma membrane. This allows the coated vesicle to …show more content…
Then clathrin and adaptin disassemble from the vesicle, which then leaves the vesicle uncoated. The vesicle then fuses with an early endosome. (pg. 344) The endosome then takes the vesicle apart and separates the receptor from the protein. Then the late endosome pinches off the part that holds the receptor and sends it back to the plasma membrane to be recycled. The protein is then transferred to a lysosome where it breaks it down to be used by the cell. (pg. 345 Figure 12-15)
Question #7 from D2L: What are peroxisomes? Where do you find them? What role do they play in cellular metabolism? Explain their role in hydrogen peroxide metabolism.
Peroxisomes are single membraned organelles that contain the enzyme catalase, which is responsible for the breakdown of hydrogen peroxide. Eukaryotic cells typically have peroxisomes present in the cell, however they are most commonly found in the “kidney and liver
Chapter 12
Books cited: Becker’s world of the cell: J. Hardin, G. Bertoni, and L. Kleinsmith: 8th edition; pgs.343-345 & pgs. 356-358
Question #5 from D2L: What is receptor mediated endocytosis? Explain how it occurs.
Receptor meditated endocytosis is a way the cell uses endocytosis by absorbing coated vesicles by the means of clathrin and breaking down the absorbed materials so the cell can use it. Receptor mediated endocytosis begins by the binding of a protein to a receptor that is located on the plasma membrane. Next the receptors collect and cluster in coated pits, and then forms a vesicle.(pg. 343) Then adaptin binds to the receptor and clathrin then binds to adaptin, which then makes a shell that surrounds the outside of this vesicle. The protein dynamin causes it to detach from the plasma membrane. This allows the coated vesicle to …show more content…
Then clathrin and adaptin disassemble from the vesicle, which then leaves the vesicle uncoated. The vesicle then fuses with an early endosome. (pg. 344) The endosome then takes the vesicle apart and separates the receptor from the protein. Then the late endosome pinches off the part that holds the receptor and sends it back to the plasma membrane to be recycled. The protein is then transferred to a lysosome where it breaks it down to be used by the cell. (pg. 345 Figure 12-15)
Question #7 from D2L: What are peroxisomes? Where do you find them? What role do they play in cellular metabolism? Explain their role in hydrogen peroxide metabolism.
Peroxisomes are single membraned organelles that contain the enzyme catalase, which is responsible for the breakdown of hydrogen peroxide. Eukaryotic cells typically have peroxisomes present in the cell, however they are most commonly found in the “kidney and liver