Declarative Memory Analysis

We experience the process of thinking and our intentions as self-determining from our bodily functions. Conscious events are a reflection of our brains functions. Consciousness is the awareness of thoughts, perceptions, memories, and feelings. Memory is one of the most important functions we use every day. Characteristics of declarative memory as well as spatial memory and long term memory all have a role in the hippocampus. Also responsible for our memory, ageing and dementia is acetylcholine.

Declarative memory is the storage and conscious recollection of events occurring in a particular place and time. Declarative memory involved the ability to form associations and retain relational information across time. Facts and events are able
Long term Potentiation also known as LTP is the leading model of synaptic changes that underlie learning and memory. This occurs when the synapse is active and the postsynaptic cell is depolarized. Cells that lead to the synapse onto the dentate granular cells are called DG cells which then send axons to CA3. CA3 cells are responsible for sending axons to CA1 output cells. LTP has four crucial steps to making the process obtainable. One glutamate the neurotransmitter to the CNS is released allowing acts on both AMPA and NMDA receptors. Sodium receptors are then able to flow through the AMPA. Next the depolarization of postsynaptic cells relieve the MG2 block to the NMDA. This allows sodium and calcium to flow to the dendritic spine. Thirdly the increase of calcium binds to calmodulin to activate calmodulin kinase which then undergoes autophosphorylation. Which means they become more sensitive to glutamate and promotes movement to the AMPA receptors. Lastly the entry of calcium activates PK which phosphorylates to CREB, resulting in nitic oxide synthase. This means no synthesis is produced, and the presynaptic terminal facilitates glutamate release. The increase of glutamate and AMPA result in a faster and stronger
The role of acetylcholine (ACh) is the first identified neurotransmitter. This means when Ach is released into the hippocampus this allows for a electrical signal to go to the brain being called hippocampus theta. Hippocampus theta occurs during exploration or investigation behavior. Theta activity is processed to the dentate gyrus and CA3 field allowing information to be sent to the CA1 field. During a deep sleep the CA1 information is transferred to the neocortex where long term memories can be