Pre-Assignment #2
1. Describe three patterns of chromosomal breakage and rearrangement.
a. Three patterns of chromosomal breakage and rearrangement are deletion, balanced translocation, and isochromosomal translocation. Deletion is when part of a chromosome is lost affects its length and genetic composition. Translocation is when there is a coinciding break in two chromosomes in different parts resulting in exchange. Balanced translocation is when two homologous chromosomes break and exchange the acentric fragment (a part of the chromosome that doesn’t have a centromere). Isochromosomal translocation occurs when one part of the chromosome is lost and another part is replicated.
2. Cite the most susceptible period of intrauterine