Jordan Rees
Hepatitis C has infected over 130million people world-wide and is an infectious disease normally affecting the liver and is sometimes asymptomatic, which means that the carrier or person affected would experience no symptoms. It is caused by the hepatitis C virus or HCV for short and lives in liver cells.
HCV is a not a casually transmitted disease, so it can’t be spread by kissing, hugging, touching, sneezing etc. it is transmitted through blood or blood to blood contact such as sharing needles, or other items that come in contact with a carrier of HCVs blood such as tooth brushes, razors and so on. In rare cases HCV can be obtained through sex and in some very rare cases it is passed down through child birth.
On a cellular level HCV invades the human liver cells to survive and spread. Researchers have found out that hepatitis C binds with a components of cellular metabolism, microRNA to help protect and spread the virus. The virus dissolves its protein coat to release viral RNA into the liver cell. The viral RNA then begins to make what is necessary for the reproduction. As this is happening the virus also possibly shuts down normal functions of the cell, the viral RNA will then synthesize the RNA transcriptase it will need to reproduce, after this the viral RNA will make and antisense version of itself as a template for the creation of new viral RNA.
Symptoms of Hepatitis C include fatigue, loss of appetite, nausea, joint paint and weight loss and can lead to cirrhosis or liver cancer and in some rare cases an acute liver failure if nothing is done.
Treatment for hepatitis C, depending on the genotype, medication is recommended, an anti viral drug called ribavirin to be taken twice a day from in between 24-48 weeks and a weekly Pegylated interferon injection. To prevent yourself from getting infected with Hepatitis C from another person don t do drugs or share needle equipment, don’t share items could possibly come
References: 1. http://en.wikipedia.org/wiki/Hepatitis_c 2. http://en.wikipedia.org/wiki/Hepatitis_c#Signs_and_symptoms 3. http://www.hepatitisaustralia.com/__data/assets/pdf_file/0010/2350/Guide-to-hepatitis-C-treatments.pdf 4. http://www.bupa.com.au/health-and-wellness/health-information/az-health-information/type-1-diabetes