Experiment 1
Acid-Base Titrations: Analysis of Antacid Tablets
Cuenca, Carlo Nicolo B.
Del Prado, Rockson D.
MEB21
Bachelor of Science in Biology – Major in Medical Biology
College of Science
De La Salle University – Dasmariñas
Dasmariñas, Cavite Philippines
ABSTRACT
This experiment was performed to learn the technique of acid-base titration and to compare the efficiency of commercially available antacids by looking at their weight of HCl and weight of antacid values. The analysis of antacid tablets was highlighted in this experiment. The efficiency of antacid tablets was determined and compared when the number of grams of HCl can be neutralized by 1 gram of the tablet was found. First, the two antacid tablets (Kremil-S) were crushed and weighed to the nearest 0.01 g which was 0.5003 g and 0.5014g. Then, transferred into a 250 mL flask and added 50.0 ml 0.1M HCl using an acid burette. Then, the antacid was dissolved in the acid. After that, the two drops of phenolphthalein indicator were added and was mixed thoroughly. Lastly, the antacid mixture was titrated with 0.1 M NaOH the solution turned to a faint pink color. Recorded the final volume of NaOH used. Here, two trials were done. After the procedures, the weight of HCl that reacted with 1 gram of antacid tablet was calculated and found the result of 0.31 HCl per gram of antacid tablet. With the recovered amount of HCl, it was found out that the antacid tablet (Kremil-S) that has been tested were not so efficient. The experiment that has been conducted only shows how antacid tablets counteract acidity by reacting with the excess hydrochloric acid in the stomach and its effectiveness as one of the most widely used self-prescribed medicine.
INTRODUCTION
Antacid tablets are probably one of the most widely used self-prescribed medicines. They are taken to relieve the medically underlined conditions of heartburn on acid indigestion and sour stomach. Excessive hydrochloric acid in the stomach causes a
Cuenca, Carlo Nicolo B.
Del Prado, Rockson D.
MEB21
Bachelor of Science in Biology – Major in Medical Biology
College of Science
De La Salle University – Dasmariñas
Dasmariñas, Cavite Philippines
ABSTRACT
This experiment was performed to learn the technique of acid-base titration and to compare the efficiency of commercially available antacids by looking at their weight of HCl and weight of antacid values. The analysis of antacid tablets was highlighted in this experiment. The efficiency of antacid tablets was determined and compared when the number of grams of HCl can be neutralized by 1 gram of the tablet was found. First, the two antacid tablets (Kremil-S) were crushed and weighed to the nearest 0.01 g which was 0.5003 g and 0.5014g. Then, transferred into a 250 mL flask and added 50.0 ml 0.1M HCl using an acid burette. Then, the antacid was dissolved in the acid. After that, the two drops of phenolphthalein indicator were added and was mixed thoroughly. Lastly, the antacid mixture was titrated with 0.1 M NaOH the solution turned to a faint pink color. Recorded the final volume of NaOH used. Here, two trials were done. After the procedures, the weight of HCl that reacted with 1 gram of antacid tablet was calculated and found the result of 0.31 HCl per gram of antacid tablet. With the recovered amount of HCl, it was found out that the antacid tablet (Kremil-S) that has been tested were not so efficient. The experiment that has been conducted only shows how antacid tablets counteract acidity by reacting with the excess hydrochloric acid in the stomach and its effectiveness as one of the most widely used self-prescribed medicine.
INTRODUCTION
Antacid tablets are probably one of the most widely used self-prescribed medicines. They are taken to relieve the medically underlined conditions of heartburn on acid indigestion and sour stomach. Excessive hydrochloric acid in the stomach causes a
References: (1) Samonte, J.L & Figueroa L.V. 2007. General Chemistry Laboratory Manual 3rd Edition. C & E Publishing Inc. Quezon City Philippines (2) Masterton, W.L, Hurley C.N, Neth, E. 2012. General Chemistry. Philippine Edition. Pasig City, Philippines: Cengage Learning Asia Pte Ltd. (3) Chang, R., 1998. Chemistry. 6th ed. NY: WBC McGraw Hill (4) Web-based reference: http://www.ehow.com/facts_4857155_what-antacid.html Retrieved: September 29, 2012