Aim: To visit a microbiology department at the university hospital and acquire detailed information of various antigen-antibody tests eg. ASO, haemotoglutination, ELISA etc. Method: To listen to presentation made and thus formulate a concise report on that which was discussed and demonstrated. (Please see BC34D Laboratory Manual for more information)
Concise Report/Summery:
The term serology refers to both the study of general antigen-antibody reactions in a laboratory setting and the specific blood test conducted to test for the presence of antibodies. A serology test is performed to determine a patient's blood type and to test for and identify an infection, giving serology applications in the fields of health care and criminology. The blood test can be either qualitative, to see if there are antibodies, or quantitative, to determine the levels of antibodies in the blood. Agglutination and precipitation tests are performed to determine the type of infection. The agglutination test involves taking the culture of antigens mixed with antibodies and examining it under a microscope to see if clumping occurs. The precipitation test determines the similarity of antigens. The antibodies are placed in agar gel with the antigens. A line forms where the two interact. Antigens are microorganisms that have the potential to cause infection in the body. When the body is exposed to an antigen, it produces antibodies that are designed to fight the specific antigen invader. Sometimes, antigens are present in the blood, but there is no apparent infection. In this case, serology tests can be performed to test the levels of antibodies in the blood; if the levels increase, the body is fighting an infection. Serology the science may be complex, but for a patient undergoing a serology test, it is as simple as getting your blood drawn. Either a nurse or a doctor performs the test in a clinical setting. The risks are the same as any other blood draw: