It happens when high blood glucose has a damaging effect on the kidneys. In the body, one of the effects of high glucose levels that extra water is pulled in the blood stream, which increases blood pressure. High blood pressure affects the nephrons, designed to filter water and certain waste products from the blood, in the kidneys. In an amount of time, the amino acids and proteins are able to escape into the urine through pores which is an indication of kidney dysfunction, which later can become a kidney failure. The damages that occur in the kidney are permanent. Kidney transplant might be needed to survive when patients start to experience swelling in the legs.
Diabetic Neuropathy, the areas where the nerves are damaged, are very common. It's caused by the high concentration of glucose. It can cause a patient to lose the control of an area in the body. The common areas are either the arm, feet or even both. Diabetics frequently feel numbness, tingling or even burning in their feet, and it can make the diabetic to injure themselves without them noticing. Cuts and blisters can turn to pressure sores, which become infected and very difficult to heal. These sores can cause the patient to lose a leg, foot, and even can cause the patient to