Lactate Experiment

The aim of the experiment was to examine the effects of consuming lactate before and during a prolonged exercise. The data shows that the consumption of the lactate actually did work and the performance of the subject was better than the previous three experiments of dieting. This was due to the lactate that was consumed in the CytoMax. Azevedo, Tietz, Two-Feathers, Paull, and Chapman (2007) state that CytoMax contains polylactate which speeds up the delivery of substrates and is thought to help with prolonged exercise. They believe that polylactate will the delay of fatigue and provide energy for the body. In the experiment this can be observed because after the initial drop of blood glucose in the first fifteen minutes of exercise from 77.2mg/dL
This makes sense because type II fibers are high glycolytic fibers and type I fibers are oxidative fibers. Brooks (1985) showed this concept by using isotope racers to follow lactate. The study was conducted on rats, where a lactate tracer was infused into the blood of the rats. He took blood from the rats at rest and during exercise to see what happens to the rats blood lactate. The observation that was made was the lactate was being produced and consumed. He believed that about half of the lactate that was produced at rest was being oxidized. In Brooks et al. (1991) the study was performed on men and women to find the same result, that at rest the lactate produced and about half was oxidized. The only difference in this study it was shown that at 50-75% of the VO2 max the body can oxidize about 75-80% of the lactate. Messonnier et al. (2013) explained that the metabolic clearance rate is influenced by the intensity the body is working at. From light to moderate intensity, the body’s rate is high meaning the body can consume the amount of lactate that is being produced but when the body moves from moderate to high intensity the clearance rate decreases. With the increase in intensity causes more type II fibers to be activated causing more lactate to potentially to be formed. This means the body can no longer consume the
In a research article Schruers and Schaafsma (2010) talked about how the lactate is transported from the cytosol to the mitochondria and the transporter is called monocarboxylate transporter (MCT). This transporter has various forms and varies in different areas in the body. In the article, they mentioned that the body has three main MCT: MCT1, MCT2, and MCT4. The location of MCT4 is in the fiber type II (fast twitch muscle) and not in type I fibers. It is known to be involved in the efflux of lactate from muscle fibers. MCT1 is different, because this MCT is found in type 1 fibers and type IIa fibers. This transporter is the transporter that consumes the lactate. MCT2 is the transporter that helps consume the lactate that is formed at rest and is thought to be in the heart. In the review article Cruz et al. (2012) examined two main areas where lactate consumption occurs the heart and skeletal muscle. In the article, they combed through studies to examine what is occurring in these sites. They concluded that the mitochondria are able to oxidize the lactate directly because of the MCT1. That the lactate that is being produced in the muscle can be transported because of the MCT1 and once in the mitochondria the lactate can turn into pyruvate because of