Bibliography sites/ references http://www.news-medical.net/health/What-is-Leprosy.aspx http://www.sciencemag.org/content/308/5724/1040.full?sid=b8d5b987-ab6e-4e10-a253-ff2ad196ad0c http://cmr.asm.org/content/19/2/338.full http://www.stanford.edu/class/humbio103/ParaSites2006/Leprosy/snsx.htm http://www.stanford.edu/class/humbio103/ParaSites2005/Leprosy/clinical.htm *
2. Name and Description of disease
Hansen’s Disease or Leprosy
Incubation period – last anywhere from 2 to 10 years (http://www.news-medical.net/health/What-is-Leprosy.aspx)
Incubation period: The incubation period for leprosy is variable and difficult to define. The onset of leprosy is usually insidious in nature (TT usually develops over 3 or more years and LL over 8 or more years.) Incubation periods as long as 30 years have been reported among war veterans who were in areas of endemic infection during military service but otherwise resided in non-endemic areas. On the other hand, incubation periods as short as just a few weeks have been observed in the occurance of leprosy among young infants. (http://www.stanford.edu/class/humbio103/ParaSites2005/Leprosy/clinical.htm)
Signs/ Symptoms
Lesions,(occur on areas of the body with a cooler temperature) skin blemishes, scaly patches, light skin color, hair loss, numbness, eye damage (reduced blinking), dryness, sensation of touch, temperature, and pain are lost. Thickened peripheral nerves pain can exist, pins and needles sensation (paresthesia)severe pain on infected limbs hypopigmented macules (flat, pale areas of skin)
3. Name of Organism that causes disease: Mycobacterium leprae
4. Pathology (http://www.atsu.edu/faculty/chamberlain/Website/lectures/tritzid/leprosy.htm) an acid fast, Gram+, rod-shaped obligate intracellular organism. Grown in armadillos. It cannot be grown in an agar medium. The earliest clinically detectable lesions of leprosy involve the skin and show histologic