Metastatic Prostate Cancer

This disease could be looked at as both localized and metastatic. Prostate cancer that started in the prostate gland and has not spread to any other place in the body. This is called localized prostate cancer. This type of cancer is treatable, and does not really have much of a deadly effect on men who have contracted the disease. It is the first and second stages of prostate cancer in all men. This kind of cancer can be treated in three different ways; surgery, radiation therapy, and active surveillance. The more advanced type of prostate cancer is Metastatic prostate cancer. This form of cancer occurs when the cells break away from the tumor in which it has originally started in. Metastatic prostate cancers are composed of both androgen-dependent
and androgen-independent malignant cells. Androgen-dependent cells, require a critical level of androgen to activate a satisfactory amount of androgen receptors. This is so genes such as death-signaling genes can be transcribed and transported. Therapies, such as androgen ablation permit the specified genes to be introverted. This motivates biochemical forces, causing apoptotic cell death, leading to destruction of other androgen-dependent cells.