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PCN501

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PCN501
Pharmacotherapy Chart

Addictive Drug
Treatment Drug
Explain how the drug is used to treat addictive and substance use disorders
Describe applications of use in co-occurring disorders
Evaluation of the drug’s effectiveness in treating addictive and substance use disorders
Nicotine
Nicorette
Helps to reduce nicotine cravings; considered as replacement therapy
None
NRT’s increase the rating of quitting by 50-70% (Capuzzi, et al, 2011)
Oxycodone
Methodone
Methadone is a long-acting synthetic opioid agonist medication that can prevent withdrawal symptoms and reduce craving in opioid-addicted individuals. It can also block the effects of illicit opioids. It has a long history of use in treatment of opioid dependence in adults and is taken orally.
Combined with behavioral treatment: Research has shown that methadone maintenance is more effective when it includes individual and/or group counseling, with even better outcomes when patients are provided with, or referred to, other needed medical/psychiatric, psychological, and social services (e.g., employment or family services).

Alcohol dependence
Naltrexone
Naltrexone is an opioid antagonist that is approved for the treatment of both opioid dependence and alcohol dependence. In people with alcohol dependence, it is believed that this blockade (opioid antagonism) diminishes craving for alcohol and leads to a greater ability to resist urges to drink excessively.

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