Activity 1: Effect of Arteriole Diameter on Glomerular Filtration
1. Compare this data with your baseline data. How did increasing the afferent arteriole radius affect glomerular filtration rate?
>>Increasing the afferent arteriole radius pushed the glomerular pressure, the glomerular filtration rate, and the volume of urine to be higher than the baseline data. Increasing the afferent arteriole radius increased the glomerular filtration rate. 2. Under these conditions, does the fluid flow through the nephron?
>>No! No urine was collected which indicates no fluid flows through the nephron.
3. What is the glomerular filtration rate?
>>The glomerular filtration rate is 0 which means the glomeruli are not carrying out any filtration task. 4. How does it compare to your baseline data, and why?
>>The glomerular filtration rate in baseline data is 124.99 which indicate functional glomeruli. The data support the concept that the reduction of the size of the afferent radius will definitely affect the glomerular filtration functions. With significant reduction of the afferent radius, very limited blood can pass through the capillaries and that leaves insufficient fluid to be filtered no any extra water can be produced as urine. 5. How did increasing the efferent radius affect glomerular filtration rate?
>> Increasing the efferent radius decreases the glomerular filtration rate. Increasing the efferent radius allows more blood drainage out of the glomerulus and that decreases the amount of blood to be filtered so the glomerular filtration rate will decrease.
6. How did decreasing the efferent radius affect glomerular filtration rate?
>> Decreasing the efferent radius increases the glomerular filtration rate. The constriction of the efferent radius will limit blood drainage out of the glomeruli and that requires increasing the glomerular filtration rate.