Good afternoon everyone. Today, I would like to talk about Effects of steroid ointment application on chemotherapy-induced phlebitis by A randomized, double-blind, placebo-controlled clinical trial.
We have nothing to declare for this research.
Phlebitis is a very common side effects of continuous intravenous infusion of 5-fluorouracil via the peripheral veins.
We evaluated the preventive effects of topical steroid application on fluorouracil-induced phlebitis by randomized, double-blind, placebo-controlled clinical trial.
The photo shows phlebitis of a patient who underwent cisplatin chemotherapy via the peripheral vein.
Phlebitis causes two big problems about nursing and cosmetic.
In nursing, nurses cannot use the damaged vein for anticancer drug infusion and they should use another vein for next infusion. From the view point of cosmetic, the appearance of forearm will change with phlebitis and it causes stigma of cancer or chemotherapy. It might restrict the patients’ quality of life especially in the activities with light dressing.
The present study is a randomized, double-blind, parallel-group, placebo-controlled trial. …show more content…
After the informed consent, registered subjects were randomly allocated into a placebo control group in whom provided petroleum jelly or an intervention group in whom petroleum jelly plus steroid ointment application. Patients applied the allocated ointment on the forearm by themselves every morning and evening during CF therapy. As this photo, the allocation areas were defined within a range of insertion site to 15cm. CF therapy needs 4 or 5days and we evaluated the pigmentation and induration at 24 hours and 1 month at after the CF therapy. The primary endpoint was the pigmentation length at 28 days after the end of FP therapy. Assessments requiring measurements were performed by two