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Our Lady of Fatima University

IN VITRO DETERMINATION OF THE ANTHELMINTIC PROPERTY OF FORMULATED SYRUP FROM CYPERUS ROTUNDUS, CYPERACEAE (BARSANGA) CRUDE EXTRACT

An Undergraduate Thesis
Presented to the Faculty of the College of Pharmacy
Our Lady of Fatima University

In partial fulfillment of the requirements for the Degree
Bachelor of Science in Pharmacy

By:
Arellano, Angelique Dominika M.
Bernas, Karol C.
Cabulay, Ivy Mariz C.
Calimpusan, Charisse B.
Dela Cruz, Francheska Annel J.
Diaz, Eva B.

March 2014
Our Lady of Fatima University

CHAPTER 1 INTRODUCTION

Intestinal parasitism is rampant in the Philippines especially in rural areas where health care is often the least priority. This disease is frequently overlooked since the infected individuals are often asymptomatic unless the infection is severe enough to cause obvious signs of infection such as abdominal enlargement or actual passage of worms from orifices. Intestinal parasitism is a persistent problem in our community and it is precipitated by poor sanitation and hygiene, and limited supply of clean water. According to DOH, the most affected are the children ages 2-14 years old and the common consequences of intestinal parasitic infections have shown to affect their nutritional status, physical development and mental function.
One of the programs of DOH named “Garantisadong Pambata” schedules two rounds of deworming annually, which covers pre-school and elementary pupils and is primarily administered through local barangay health units, trained barangay healthworkers, and day care workers. They are using mebendazole or albendazole tablets for deworming. The DOH claims that reinfection is 100% at 6 months after treatment, hence the need for treatment is at least twice a year.
Some NGO’s have come up with some ideas to address the growing population of infected individuals with intestinal parasites and to solve the problem to its root cause. They have used



References: Muyargas, N.M.A. 2011. The Effect of Ipil-Ipil seed treatment on the reinfection of soil-transmitted Helminthiasis(STH) among children ages 2-14 in three different municipalities in Zamboanga Peninsula. Ateneo de Zamboanga University School of Medicine. Iqbal, Z. et al. 2001. In Vitro Anthelmintic Activity of Allium sativum, Zingiber officinale, Cucurbita mexicama and Ficus religiosa. College of Veterinary Sciences, Lahore-pakistan. Ghannadi, A. et al. 2012. Phytochemical screening and essential oil analysis of the Persian sedges; Cyperus rotundus L. Department of Biology, Faculty of Sciences, Isfahan University, Iran. Rama, D. et al. 2010. Phytochemical screening and anthelmintic activity of Crotalaria pulchra (Andr). Pulla Reddy Institute of Pharmacy, India. Gupta, R. et al. 2013. Investigation of In vitro anthelmintic activity of Ficus elastic leaves. Department of Pharmachemistry, Pharmacognosy, Pharmaceutical Institute of Science and Technology, Jabalpur. Quisumbing, E. (©1978). Medicinal Plants of the Philippines (Vol. |Vol. 1 |Issue 1 ). Quezon City, Philippines: JMC Press, Inc. Khemani, L.D. et al 2012. Chemistry of Phytopotentials: Health, Energy and Environmental Perspectives. Springer-Verlag Berlin

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