Critical Thinking Assignment
CT Assignment
1. The title of the article is Metformin and Exercise in Type 2 diabetes, the author is Boule and others, 2011, the audience is intended for probably other scientists, and the type of article is a research report because it was a experiment conducted and the research was reported.
2. I. Reason for the study
i. To see the correlation between exercise and metformin separately and their affects. ii. To see if taking metformin and doing exercise and what the effects of this is.
II. Perform the experiment
i. Ten volunteers with type 2 diabetes, the four conditions that the volunteers were tested under were, metformin and no exercise, metformin and exercise, placebo and no exercise, and placebo and exercise. ii. They participants were monitored in a number of ways
III. Results
i. Some reported mild gastrointestinal side effects, all participants except for one were able to tolerate the full dosage. ii. Participants did not report any difference in symptoms such as abdominal discomfort between conditions.
IV. Conclusion
i. Metformin increased lipid oxidation, shown by lower RER during all three submaximal intensities of exercise. Maximum metformin concentrations were reached 120-140 min after dosage. ii. These results show that the combination of metformin and exercise are actually less affective.
3. The basic question or problem that this article addressed is the effect of metformin with exercise, and also how it effects the plasma metformin concentrations.
4. Determine effect of metformin on the acute metabolic response to submaximal exercise, the effect of exercise on plasma metformin concentrations, and the interaction between metformin and exercise after a meal.
5. There was not a clear hypothesis given, I think that they had a subject that needed studied and decided to do an experiment and see the correlation to it.
6. The experimental design was to get 10 participants and then using the variables test the correlation to
1. The title of the article is Metformin and Exercise in Type 2 diabetes, the author is Boule and others, 2011, the audience is intended for probably other scientists, and the type of article is a research report because it was a experiment conducted and the research was reported.
2. I. Reason for the study
i. To see the correlation between exercise and metformin separately and their affects. ii. To see if taking metformin and doing exercise and what the effects of this is.
II. Perform the experiment
i. Ten volunteers with type 2 diabetes, the four conditions that the volunteers were tested under were, metformin and no exercise, metformin and exercise, placebo and no exercise, and placebo and exercise. ii. They participants were monitored in a number of ways
III. Results
i. Some reported mild gastrointestinal side effects, all participants except for one were able to tolerate the full dosage. ii. Participants did not report any difference in symptoms such as abdominal discomfort between conditions.
IV. Conclusion
i. Metformin increased lipid oxidation, shown by lower RER during all three submaximal intensities of exercise. Maximum metformin concentrations were reached 120-140 min after dosage. ii. These results show that the combination of metformin and exercise are actually less affective.
3. The basic question or problem that this article addressed is the effect of metformin with exercise, and also how it effects the plasma metformin concentrations.
4. Determine effect of metformin on the acute metabolic response to submaximal exercise, the effect of exercise on plasma metformin concentrations, and the interaction between metformin and exercise after a meal.
5. There was not a clear hypothesis given, I think that they had a subject that needed studied and decided to do an experiment and see the correlation to it.
6. The experimental design was to get 10 participants and then using the variables test the correlation to