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history of biomaterials
CYL458: Biomaterials

History of biomaterials
Yashveer Singh, PhD
Department of Chemistry

20 May 2014

1

Suggested readings
 Biomaterials – The Intersection of Biology and Materials Science,
JS Temenoff and AG Mikos, Prentice Hall, 2009
 Biomaterials Science: An Introduction to Materials in Medicine,
BT Ratner, AS Hoffman, FJ Schoen, JE lemons (Eds), CRC Press,
Boca Raton, FL, 1996

2

History of biomaterials

http://northwestportlanddental.com/d ental-services/restorative-dental-care/ 2000 years ago: The Romans and Chinese used gold in dentistry and through much of the history, use of glass eye and wooden teeth has been recorded 1860s: The use of biomaterials did not become practical until the advent of an aseptic surgical technique developed by Dr J. Lister. Earlier surgical procedures, whether they involved biomaterials or not, were generally unsuccessful as a result of infection
Biomaterials, Joyce Y Wong and Joseph D Bronzino (Eds), CRC Press, Boca Raton, FL, 2007

3

History of biomaterials
1900s: Bone plates were introduced to aid in the fixation of long-bone fractures. Many of these early plates broke as a result of unsophisticated mechanical design; they were too thin and had stress-concentrating corners.
Also, materials such as vanadium steel, which was chosen for its good mechanical properties corroded rapidly in the body and caused adverse effects on the healing processes
1930s: Stainless steels and cobalt chromium alloys were introduced and great success was achieved in fracture fixation, and soon joint replacement surgeries were performed

Biomaterials, Joyce Y Wong and Joseph D Bronzino (Eds), CRC Press, Boca Raton, FL, 2007

4

History of biomaterials

PMMA

1940s: During the World War II, it was found that pilots injured by fragments of plastic PMMA (polymethyl methacrylate) aircraft canopy did not suffer adverse chronic reactions from the presence of the fragments in the body. PMMA

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