Acetaminophen Data: p-aminophenol: 0.150g Weight of crude acetaminophen 0.122g Weight of purified acetaminophen 0.060g Weight of crystallized acetaminophen 0.028g Melting point range for dried crude product 166.8-167.6°C Melting point range for final crystallized product 166.1-169.8°C Melting point range for pure Acetaminophen 169.5-171°C Results: After first isolation of crude acetaminophen‚ 1.22g of
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Ibuprofen and Acetaminophen Organic chemical compounds contain a vast number of isomers‚ molecules with the same molecular formula but different atomic arrangement‚ of which there are three types: structural‚ geometric and optical. The most closely-linked of isomers are optical isomers‚ which differ only by the three-dimensional placement of the molecule’s attachments‚ which renders its mirror images to be non-superimposable. The presence of optical isomerism within a molecule is determined by
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Acetaminophen Abstract: The aim of this experiment is to prepare Acetaminophen (p-acetamidophenol)‚ an amide. Acetaminophen will be created by treating an amine (p-aminophenol) with an acetic anhydride. Color impurities present in the solid acetaminophen will be removed and then the decolorized product will be collected on a Büchner funnel for further purification by crystallization. Purity will then be determined by melting point. Introduction: Acetaminophen is commonly used as an analgesic to
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Chemistry Synthesis of ACETAMINOPHEN Laboratory Report 1 CHEM 123L January 19‚ 2014 Prepared for: Dr. S. Stathopulos Department of Sciences‚ Chemistry Faculty University of Waterloo Teaching Assistant: Aaron Chan Prepared by: Section 001 Vithurjan Satkunarasan 20495383 Lab Partner: Ken Xu Introduction The synthesis of Acetaminophen is based on the amine group of p-aminophenol being acetylated by acetic anhydride to form an amide functional group. Acetaminophen is isolated as a crude solid
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Experiment 1 Synthesis of Acetaminophen Clifford Tse 20529845 Partner – Raminder Dhanoa TA – Xiao Qi CHEM 123L - 012 February 6‚ 2014 Introduction Acetaminophen‚ also commonly known as Tylenol‚ is an over-the-counter medicine used to relieve pain and reduce fevers. Within this experiment‚ Acetaminophen will be formed through the reaction between p-aminophenol and acetic anhydride. This reaction will incur Acetaminophen as a crude solid being impure‚ which will be purified further through
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Introduction: Acetaminophen is a commonly used analgesic‚ which is essentially just a medicine that relieves pain (Prescott‚ 2000). Acetaminophen is created by synthesizing p-Aminophenol with Acetic anhydride. This reaction occurs when the amine group of the p-aminophenol is acetylated by the acetic anhydride. The resultant is an amide functional group (Ellis‚ 2002). However‚ the product that is obtained from this product is a crude solid which cannot be used as an analgesic and therefore the crude
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Some consumers want to know if acetaminophen dissolves faster in the form of tablets‚ gelcaps‚ or caplets in order to get the fastest pain relief. The purpose of this experiment was to find out which of the three tested forms of acetaminophen would dissolve the most over a time period ten minutes. The hypothesis stated that the tablets would dissolve the most over the ten minutes. The hypothesis was tested by dropping ten of each of the forms of the acetaminophen into two thirds a cup of boiling
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Small samples of acetaminophen‚ acetylsalicylic acid‚ cellulose‚ starch‚ and caffeine were obtained. These samples were then placed into seperate sets of test tubes that contained water‚ acetone‚ or dichloroethane. Solubilities were then tested for each sample in each solution which can be seen in Table 5. Next‚ four random pills were obtained and weights were taken of each. Each of the pills were grinded up using a separate mortar and pestle. The grinded up pills were then weighed. The grinded
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Drug Store Items Knowns Rf Values Aspirin .91 cm Acetaminophen .85 cm Ascorbic Acid .86 cm Unknown .97 cm Identity of unknown mixture Acetaminophen Analysis of Paprika Pigments Spot Number Rf Color 1 1 Red-orange 2 1 Red-orange Calculations A. Analysis of Paprika picture sample B. Flower sample for paper chromatography Analysis of Drug Store Items Knowns Rf Values= a/f Aspirin 7.0/7.7= .91 cm Acetaminophen 7.7/7.7= 1 cm Ascorbic Acid 6.6/7.7= .86 cm Unknown
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Experiment 3: The preparation of acetaminophen (paracetamol) with thin layer chromatography (TLC) to monitor the reaction. Abstract: This experiment is to demonstrate the preparation of paracetamol and its properties. Reflux and filtration of 4-aminophenol and acetic anhydride formed the crude sample. Further analysis of dry white crystals were used to give quantitative measurements and a percentage yield of 46% was obtained. The overall conclusion is that the acetic anhydride reacted with the
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