PATHOPHYSIOLOGY OF MYOCARDIAL INFARCTION Mechanisms of Occlusion Most MIs are caused by a disruption in the vascular endothelium associated with an unstable atherosclerotic plaque that stimulates the formation of an intracoronary thrombus‚ which results in coronary artery blood flow occlusion. If such an occlusion persists long enough (20 to 40 min)‚ irreversible myocardial cell damage and cell death will occur.5 The development of atherosclerotic plaque occurs over a period of years to decades
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Mercy Hospital is celebrating the gift of life for many through a program called Mercy Variety Yucatan Heart Program. This program was started back in 1979 (Mercy‚ 2009). It has grown throughout the years and now has benefited almost 900 children. A lot of time‚ effort‚ money‚ and planning goes into this project. Each February a team of doctors‚ nurses‚ and clinical staff travel to the cities of Campeche and Merida in the Yucatan Peninsula of Mexico. This team then opens a week long clinic for children
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|21 | Coursework R: Mini-Review Topic Selected: Topic 2: “Skeletal muscle undergoes repair and regenaration throughout normal life. Write a review on the processes involved‚ emphasizing the role of satellite cells.” Muscle Cell Regeneration and the Impact of Ageing Introduction: Throughout normal life‚ skeletal muscles undergo repair and regeneration in response to injury through a process involving several sequential steps. A very important role in this regeneration
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Bones support‚ move‚ and protect the body; they also give us our features. But without bone cells we would have no bones. Bone cells are the living units that make up your bones and keep them functioning. Bone cells have two major roles‚ which are the production of new bones and resorption or destruction of old bone. They also carry out other small roles. There are four main types of bone cells: Osteogenic‚ which are bone cells that respond to traumas‚ osteoblasts‚ which form bone matrix around themselves
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A muscle is a group of cells called fibers‚ and are generally quite big. One muscle fiber has a large amount of myofibrils‚ which are muscle proteins in the shape of cylinders. These myofibrils contain two different types of filaments‚ which run along the axis of the fiber in hexagonal patterns. The two types of filaments are thick and thin filaments. Every thick filament is surrounded by six thin filaments. Both thick and thin filaments are attached to a structure called the Z-line. The Z-line runs
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Slow-Oxidative (Type I) Muscle Fibres Shelby Daye Skeletal muscles are classified as striated and voluntary. They are found in muscles that maintain low-intensity contractions for long periods without fatigue. A single skeletal muscle cell is referred to as a muscle fibre. There are three types of muscle fibres found in the human skeletal muscle system including slow-oxidative fibres‚ fast-oxidative fibres and fast-glycolytic fibres. These three fibres are each defined by their biochemical capacities1
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Write your name here Candidate Number Edexcel GCE Biology Advanced Subsidiary Unit 1: Lifestyle‚ Transport‚ Genes and Health Monday 14 May 2012 – Morning Time: 1 hour 30 minutes You must have: Ruler Paper Reference 6BI01/01 Total Marks Instructions Use black ink or ball-point pen. Fill in the boxes at the top of this page with your name‚ centre number and candidate number. Answer all questions. Answer the questions in the spaces provided – there may be more space
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Long Island University Riociguat (Adempas‚Bayer) Therapeutic class: Cardiovascular Agent‚ Soluble Guanylate Cyclase Stimulators Clinical Pharmacology: Sensitizes soluble guanylate cyclase (sGC) to endogenous nitric oxide (NO) by stabilizing the NO-sGC binding. It also directly stimulates sGC independent of NO. Riociguat stimulates the NO-sGC–cyclic guanosine monophosphate (cGMP) pathway and leads to increased generation of cGMP with subsequent vasodilation Pharmacokinetics: Absorption:
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My seven-year-old face fell. Was she serious? I blinked my fragile eyelids in disbelief. I wanted to crumple to the ground and bawl my eyes out. I made my way to the dim basement with anticipation. My petite‚ frozen‚ feet rushed down the carpeted stairs. I couldn’t wait to go to my grandma and grandpa’s! I got close to no sleep the night before‚ tossing and turning at the thought of seeing my grandparents. `` We rarely got to see them anymore‚ busy with masses of schoolwork. Every day with
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What Life could have Been WARNING: use caution as this passage may require tissues! Tears stained my face as I contemplated the outcome. I could barely imagine what life would be like on the other side of this tragedy. My eyes squeezed shut‚ and I wished everything would go back to normal. My grandfather had recently been admitted to the Lancaster General Hospital suddenly‚ with the diagnoses of Congestive Heart Failure. He only had a few weeks to live‚ if he didn’t consent to have open heart
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