EXERCISE 11 Synthesis of Aspirin (Acetylsalicylic Acid from Salicylic Acid) RAQUID‚ Rency J Group 5 18L I. Introduction Due to the demand of certain reagents in the laboratory in order to perform and conduct further experiments or produce essential compounds‚ chemists continuously develop organic synthesis. This process aims to prepare and synthesize desired organic compounds from commercially or readily available ones by providing the simplest route in synthesizing the compound
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to be a drug that relives people of pain and is commonly used even today. It is synthesized from salicylic acid and ethanoic anhydride‚ both of small quantities. Phosphoric acid was used as a catalyst in the synthesis to speed up the process. Esterification is involved and the final product is aspirin with the presence of acetic acid as the byproduct. In order to create the powder form of aspirin‚ the process of crystallization was conducted and was run through vacuum filtration. After running through
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Crystallinity of SAPO-5 With Molar Composition The given mixture composition (Al: 1.3 P: 0.8Si: 1.2TEA: 100H2O ; Al: 1.3P : 0.05Si: 1.2TEA: 100H2O ; Al: 1.3P : 0.05Si: 0.2TEA: 100H2O) is used to study the overall effect of silicon in AFI framework.The SiO2 magnitude is varied mole ratio from 0 to 1.0 of the given SiO2 to Al2 .The crystals SEM images that is obtained by using various contents of silicon are representing the sample produced in the absence of silicon in reactant gel is similar to the
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Gurmu 1 Professor Joseph Engl 1302 04 September 2013 In the Article ‘’ Nation Made of Poetry” Joannie Fischer points out that the official documents now on the display in Washington‚ DC.‚ offers one version of America’s story. This is an authorized biography of sorts‚ screened and sanctioned. Same as we have official documents marking our nation’s progress‚ there are many others that are unofficial that have steered events‚ whether by inciting‚ critiquing‚
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This experiment allowed the students to conduct the synthesis of aspirin‚ acquire the skills of recrystallisation using normal filtration and reinforce the technique of the melting point determination. The method used to synthesize aspirin was esterification by reacting salicylic acid with acetic anhydride with the presence of dehydrating agent‚ conc. sulphuric acid‚ to speed up the reaction. Having obtained the crude aspirin which was still impure‚ recrystallisation was conducted to remove the impurities
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INTRODUCTION: Carboxylic acids are organic acids characterized by the presence of a carboxyl group‚ -COOH. This acid acts as a weak acid‚ which can react with a strong base. Carboxylic acids form hydrogen bonds with many water molecules and are more soluble with one to four carbon atoms. Also‚ it may have an R group that consist of hydrogen or an alkyl group that changes its water solubility. Carboxylic acids with low molecular weight have odor at room temperature and higher molecular weight
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Exam Name___________________________________ MULTIPLE CHOICE. Choose the one alternative that best completes the statement or answers the question. 1) 1) Disregarding stereoisomers‚ how many different enols can the β-diketone CH3 COCH 2 COCH 2 CH3 form? A) 3 B) 1 C) 4 D) 0 E) 2 2) Methylamine reacts with acetophenone to yield the: A) imine. B) enamine. C) acetal. D) amide
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August 1914 was the logical conclusion of German military and expansionary plans confirmed by the September Program of 1914’ How far do you agree with this judgement? Explain your answer using sources 1‚ 2 and 3 and your own knowledge of the issues related to this controversy. (40 marks) According to the writer of Source 1‚ there is a fundamental flaw in Fischer’s assumption that Germany’s war aims already existed before the war and also caused it‚ he writes that if Fischer is right that this would
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To increase the percentage yield of ethyl ethanoate can be achieved by removing water or ester during esterification. Esterification is reversible reaction. For all reversible reactions‚ they have equilibrium constant‚ denoted by Kc. It should be the same if the reaction performed under same condition. In order to keep the Kc constant‚ the reaction will shift right
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Discussion & Error Analysis: By examining the unknown alcohol’s H NMR spectra‚ it can be deduced that the alcohol is 1-(3-methoxyphenyl)ethanol. There are three peaks that have a shift of ~7.0-7.5‚ one with integration values of 1‚ 2‚ and 1.This shows that the alcohol is a meta-substituted benzene ring. The singlet peak with a chemical shift of~ 4.7 ppm with an integration of 1 is from the hydrogen on the OH group. The peak at ~ 1.7 ppm corresponds to the hydrogen of the carbon that is attached
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