Experiment Four: Organic Synthesis of Aspirin Abstract The purpose of this experiment is to synthesize a common organic product called acetylsalicylic acid (aspirin)‚ and to become familiar with the optimum conditions needed for successful yields. Aspirin is produced from an acid catalyzed reaction between salicylic acid with acetic anhydride. The crystalline aspirin is synthesized and purified by recrystallization‚ although there is not a hundred percent yield due to sources of error. Introduction
Free Aspirin Carboxylic acid Acetic acid
Synthesis of Aspirin (Acetylsalicylic Acid) Abstract: This experiment is about the synthesis of aspirin under laboratory conditions. Aspirin is prepared by reacting salicylic acid and acetic anhydride; in the presence of sulfuric acid. After fully dissolving the salicylic acid with acetic anhydride‚ the solution is cooled and cold water is then added. Once the crystals form they are then filtered and left to dry out. There mass is measured and recorded then the yield is calculated. Introduction:
Premium Aspirin Salicylic acid Acetic acid
Aspirin Synthesis Introduction Out of all the pharmaceutical drugs in the worlds‚ aspirin is made the most. Any potential pharmacist must be familiar with synthesizing the drug. The goal of this lab is to synthesize as much pure aspirin as possible. The reactants‚ acetyl anhydride and salicylic acid‚ must react in phosphoric acid. With phosphoric acid as a catalyst‚ the reaction yields aspirin and acetic acid. The equation for the reaction is as follows: “(CH3CO)2O + HOC6H4COOH □(→┴yields ) CH3CO2C6H4CO2H
Premium Stoichiometry Reagent Aspirin
Liquid Chromatography Analysis of Aspirin Problem: Was aspirin (acetylsalicylic acid) successfully synthesized? Are there impurities or by-products present in the synthesized aspirin? How pure is the synthesized aspirin? Introduction: In the last experiment‚ aspirin was synthesized followed by characterization of the product using several different techniques. Melting point was a test that provided information about the identity and purity of the aspirin product. The iron(III)chloride test
Premium Aspirin Salicylic acid Acetic acid
purpose of this lab is to synthesise acetylsalicylic acid (aspirin) by creating a reaction between acetic anhydride and salicylic acid. This was be accomplished through the use of recrystallization. Acetic anhydride and salicylic acid are mixed together‚ and then acidified by the addition of a few drops of concentrated sulfuric acid‚ which catalyzed the reaction. The percent yield is calculated to determine the effectiveness of the reaction in preparing the desired product (aspirin). The limiting
Premium Acetic acid Aspirin Salicylic acid
Rebecca Boreham 7/1/14 Chem 2423 Experiment #5 Synthesis of Aspirin Elizabeth Ajasa Kaylee Seymour Lauren Hatfield Suveda Perikala Introduction/ Purpose Aspirin is the most commonly used drug in the United States. Forty million pounds are produced each year. The chemical name for aspirin is Acetylsalicylic acid. Aspirin is a pain reliever and a fever reducer. Aspirin originated from the bark of a White Willow Tree. Chewing the bark however is extremely acidicand irritates the mucous membranes
Premium Aspirin Salicylic acid Acetic acid
acidity of the catalyst‚ the production of aspirin will increase. Our hypothesis was proven correct. In our data‚ we calculated the percent yield and percent error of each trial. We also calculated the average of the percent yields and the percent errors of each catalyst. In the end‚ we saw that for the sulphuric acid catalyzed aspirin‚ we saw an average of 69.7% percent yield and an average 30.3% percent error. As for the phosphoric acid catalyzed aspirin‚ we saw an average of 55.0% percent yield
Premium Aspirin Salicylic acid Acetic acid
Experimental Synthesis of Aspirin and Melting Point Purity Analysis Donald Yeargin CH 222‚ Section 24221 Department of Chemistry Portland Community College Portland‚ OR Abstract The various methods available to synthesize aspirin lead to the need to examine and evaluate production efficiency and purity. The purpose of our experiment was to synthesize acetyl salicylic acid (aspirin) and then determine the relative purity of the synthesized sample by observing the melting point temperature
Premium Aspirin Acetic anhydride Salicylic acid
Abstract: The goal of this experiment was to synthesize aspirin. In this experiment aspirin‚ also known as acetylsalicylic acid‚ was synthesized from salicylic acid and acetic anhydride. In the reaction the hydroxyl group on the benzene ring in salicylic acid reacted with acetic anhydride to form an ester functional group. This method of forming acetylsalicylic acid is an esterification reaction. Since this esterification reaction is not spontaneous‚ sulfuric acid was used as a catalyst to initiate
Premium Aspirin Acetic acid Salicylic acid
x 10-3‚ as shown in Equation 3. The purified aspirin product was a white powder that had a weight of .140 g. The number of moles of the purified aspirin product after extraction was 7.77 x 10-4 as shown in Equation 4. These two moles calculated a chemical yield of 54.3% as shown in Equation 5. The melting point of the pure aspirin product was ranged at 117.8-125.2C as shown in Table 1. An infrared spectrum for the pure aspirin from the synthesis was taken by using crushed crystals‚ Figure 1
Premium Chemical reaction Carboxylic acid Acetic acid