Jeana Greaves Chem3301-112 June 19‚ 2013 Synthesis of Aspirin from Methyl Salicylate Introduction The synthesis of Aspirin (Acetyl Salicyclic Acid) began with methyl salicylate and sodium hydroxide as the reagent. The polar oxygen accepts the electrons from now positively charged hydrogen. The positively charged sodium disassociates leaving the hydroxide ion with a negative Scheme 1 shows the mechanisms that were demonstrated during the synthesis of Aspirin. charge that attracts to the positively
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reactions of carbon-carbon bonds are important in organic synthesis [1-5]. In general‚ acylation reaction is one of the important carbon-carbon forming reactions. It belongs to the reactions of the enolate derived from a carbonyl group with an electrophilic carbon such as Aldol‚ Claisen‚ Michael reaction and alkylation of metal enolates [6-9].The acylation reaction as well as above other reactions of enolates has serious limitations to be overcome. In these reactions‚ a strong base NaOH is needed
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4255 0.001988 C14H14O2 40.02 136-138 Spectral Analysis IR Absorption (cm-1) Assignment Benzoin 3411‚ 3374 OH 2961‚ 2903 C-H aromatic 2358 C-O 1678 Ketone Compound A 3372 OH stretch 3310 OH stretch 3085‚ 3060‚ 3030 C-H stretch 2900 C-H aromatic 1451 OH bend Compound B 3371‚ 3309 C-H 2900‚ 2855 C-H stretch‚ methyl 1451 Ar C=C 1278 Acetal 1H NMR Chemical shift (δ) Multiplicity and Integration Assignment Compound B 1.6401 S‚ 3H C-CHa3
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Structural Effects on Stability and Reactivity. Organic Chemstry Laboratory Structural Effects on Stability and Reactivity Introduction The concepts of stability and reactivity are fundamental to understanding chemistry. In this chapter we consider first the thermodynamic definition of chemical stability. We then consider chemical kinetics (Section 3.2) and how it can provide information about reactivity. We also explore how structure influences stability and reactivity. We want to learn how
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|Chapter 5: | |Structure and Preparation of Alkenes. | |Elimination Reactions | Summary Alkenes contain the C=C functional group which can be prepared by 1‚2-elimination reactions such as: • dehydration of alcohols (- H2O) or • dehydrohalogenation of alkyl halides (- HX). Zaitsev’s rule indicates that the preferred product is the more highly substituted
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MARKETING REPORT Oral Care Market(India)-Mouthwash Submitted by-NISHMA VERMA 8/24/2012 This report deals with oral market of India especially the mouthwash sector. the various aspect of marketing and research and development of mouthwash product are discussed in detail. INTRODUCTION (COSMETIC MARKET) According to to a research RNCOS industrial research-The rising beauty concerns among both men and women are propelling the Indian cosmetics industry‚ which has witnessed a strong growth in
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Unsaturated Hydrocarbons Unsaturated hydrocarbons Have fewer hydrogen atoms attached to the carbon chain than alkanes. Are alkenes with double bonds. Are alkynes with triple bonds. 1 Structure of Alkenes Alkenes (and alkynes) are unsaturated hydrocarbons Alkenes have one or more double bonds The two bonds in a double bond are different: - one bond is a sigma () bond; these are cylindrical in shape and are very strong - the other is a pi (π) bond; these involve sideways overlap of
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produced using Gridnard reagent and aldehyde or carboxylate; while tertiary alcohol is produced using Gridnard reagent and ketone‚ ester‚ chloride or unsaturated ester etc. Gridnard reagent is prepared by reaction between Mg and halogenated aliphatic or aromatic halogenated‚ under common circumstances 1mol Mg is needed for 1mol of halogenated. Considered the side reactions‚ Mg should be in excess for about 10%-15%. The reactivity decrease from iodine to chlorine‚ but iodine also causes most side reactions
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Paracetamol - a curriculum resource Frank Ellis RSeC ROYAL SOCIETY OF CHEMISTRY Paracetamol - a curriculum resource Compiled by Frank E llis Edited by Colin Osborne and Maria Pack Designed by lmogen Bertin Published by the Royal Society of Chemistry Printed by the Royal Society of Chemistry Copyright 0 Royal Society of Chemistry 2002 Registered charity No. 207890 Apart from any fair dealing for the purposes of research or private study‚ or criticism or review‚ as permitted under
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and one inorganic among the unknowns. In order to have a strong background about the solubility test‚ we first classify organic compounds of known functional group using the said test. Butyl bromide‚ ethanol sucrose‚ butyraldehyde‚ ethanoic acid‚ methyl amine‚ nitrophenol‚ diethyl ether‚ benzoic acid and propanone were used. It is found out that they are class X‚ Sn‚ S‚ N‚ Sa‚ Sb‚ S‚ N‚ A1 and Sn‚ respectively. We use water‚ ether‚ HCl‚ NaOH‚ NaHCO3‚ H2SO4‚ litmus paper‚ and phenolphthalein in classifying
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