cardiac deaths before it was finally pulled off the market. Rezulin or as some know it as troglitazone was approved by the FDA in 1997. The drug was intended to treat adult onset type 2 diabetes. Rezulin did indeed lower the blood sugar pressure in rats without negative effects‚ but later the animals reportedly began to have severe and sometimes fatal liver failure. The medication still hit the market and was not withdrawn until 2000 after it causes more than 400 deaths‚ but only because Los Angeles
Premium Animal testing Animal rights Testing cosmetics on animals
Jeffrey Shenfeld An Experimental and Statistical Analysis of SDH activity as compared in Liver‚ Kidney‚ and Heart Homogenates of the Bos taurus Methods The three tissues being analyzed in this experiment‚ those of the kidney‚ heart and liver‚ were taken from the animal Bos taurus. The tissue homogenates used were made by adding 1 gram of tissue to 20 ml of sucrose phosphate buffer. The buffer was composed of 250 mM sucrose‚ 50 mM NaPO4‚ with a pH of 7.4. This mixture was homogenized with
Premium Metabolism
better (Pfunder). “Metabolism” is the last of the three projects that investigated enzymes of the skin among humans then reconstructed them into skin models. The “3D Skin Model” combined with the “Metabolism” project determined that the capacity of metabolic is compatible to that of human skin‚ with this they confirmed that the project is useful (Pfunder). There are still some cosmetic lines that continue to use animal testing for their cosmetic lines such as MAC a well know cosmetic line. MAC admits
Premium Animal testing Animal rights Testing cosmetics on animals
humans‚ which is wasteful in time‚ supplies‚ the lives of many animals. “Physiological reactions to drugs vary enormously from species to species. Penicillin kills guinea pigs but is inactive in rabbits; Aspirin kills cats and causes birth defects in rats‚ mice‚ guinea pigs‚ dogs‚ and monkeys; and morphine‚ a depressant in humans‚ stimulates goats‚ cats‚ and horses” ("Animal Testing Is Bad Science."). Even the best scientist cannot make this science
Premium Mammal Science The Animals
Green Tea and Weight Loss in Overweight and Obese Adults Introduction Obesity has become a growing health issue which is associated with increased risk of chronic diseases such as coronary heart disease‚ hypertension‚ type 2 diabetes‚ osteoarthritis‚ stroke‚ sleep apnea‚ and certain cancers (Auvichayapat et al.‚ 2008; Maki et al.‚ 2009; Nagao et al.‚ 2005). In the United States there are an estimated 72 million overweight or obese adults (as cited in Maki et al.‚ 2009). Currently‚ the most effective
Premium Obesity Adipose tissue Green tea
Focus assessment NUR-645E Griselda Richard June 18‚ 2014 Focus Assessment The purpose of this paper is to document a focused history‚ physical exam‚ nursing diagnoses‚ and nursing process of a case study about a 22-year-old woman that reports as chief complaint : feeling “sick with the flu” for the past 8 days. History of present illness : vomiting several times every day‚ having difficulty
Premium Nursing Nursing care plan
Physical Warmth‚ Interpersonal Warmth and Sympathetic Nervous System Activity La Trobe University‚ Melbourne Word Count: 2481 Abstract Convergent lines of evidence indicate that introducing a physically warm stimulus‚ such as a heat pack‚ results in individuals interpreting a target person as “warmer”. Neurobiological mechanisms responsible for thermoregulation may be shared by mechanisms responsible for interpretation of interpersonal warmth‚ and may be connected to sympathetic nervous system
Premium Temperature Energy Heat
Hindawi Publishing Corporation Mediators of Inflammation Volume 2012‚ Article ID 851798‚ 13 pages doi:10.1155/2012/851798 Research Article Adipose Tissue-Specific Deletion of 12/15-Lipoxygenase Protects Mice from the Consequences of a High-Fat Diet Banumathi K. Cole‚ Margaret A. Morris‚ Wojciech J. Grzesik‚ Kendall A. Leone‚ and Jerry L. Nadler Department of Internal Medicine‚ Strelitz Diabetes Center‚ Eastern Virginia Medical School‚ Norfolk‚ VA 23507‚ USA Correspondence should be addressed
Premium Adipose tissue Insulin Obesity
(International Diabetes Federation‚ 2011). These rates show that DM is an alarming and fatal disease throughout the world and the fact that it does not choose whatever age‚ gender‚ race or type of people there are is terrifying. Diabetes Mellitus is a metabolic disease that is characterized by an increase in normal plasma glucose level resulting from imbalance of hormones‚ insulin secretion defects‚ insulin action or all. It is the 9th out of 86 major cause of death in the whole world ( World Life Expectancy
Premium Diabetes mellitus Insulin Diabetes mellitus type 2
Introduction of case study My case study done at ward 3(female ward)‚ Hospital T and the title is bronchopneumonia‚ I choose this title because that is often occur at the ward. Patient L is a 14 years old Chinese girls and she came to hospital complaint of cough with greenish sputum as long as 2 weeks‚ she had fever at home and complaint of chest pain. She came from A&E admitted at ward 3 at 30/4/2012 (Monday)‚ 3.35pm accompanied with PPK. She admitted at the ward 3 as long as 5 days and she
Premium Pneumonia