Name: Lew Chien Ai
Radiopharmaceuticals are formulations containing radioisotopes, which are use internally for therapeutic and diagnostic purposes. Radiopharmaceuticals have modernized the medical field by their ability to provide static as well as dynamic images of internal organs in a noninvasive manner as well as by offering efficacious therapy of certain diseases.
Radioisotopes are extensively used in medicine for diagnosis, either in vivo or in vitro, for therapeutics and also for investigation purposes. Nuclear medicine (NM) studies in vivo are used to detect minimal amounts of radiopharmaceuticals in organs (the morphology) and their course over time (the function), resulting from physico-chemical interactions of the tracers within the body, in the sequence of specific physiological processes. In vitro applications of radioisotopes have become a most important tool in biochemical analysis. Therapeutic uses of radioisotopes cover from external gamma-ray sources in teleradiotherapy to direct cell irradiation in metabolic therapy.
Radioisotopes can be use in medicine in four different ways. They are:
1. Radioactive tracers for diagnostic purposes
2. Radiation source in therapy
3. Research and
4. Sterilization
The radioisotope therapy has been available to those disease conditions in which extensive cellular malfunction exists.
Diagnostic radiopharmaceuticals are used to derive detailed description of the morphology and dynamic functioning of the various internal organs of the body. The radiopharmaceutical accumulated in an organ of interest emit gamma radiation which are used for imaging of the organs with the help of an external imaging device called gamma camera.
The following are examples of radiopharmaceuticals, which are in practice worldwide for various diagnostic purposes
Abscess and infection—Gallium Citrate Ga 67, Indium In