BOI103
Lecture 1
Introduction to the Study of Cell
Course:
CELL BIOCHEMISTRY (BOI 103)
Type:
Compulsory
Total Units:
3 (3 x 1 h lecture per week)
No. of Lectures:
42
Lecturers:
1. Prof. Dr. K. Sudesh Kumar
Room 402, Block G09A PPSKH
Tel: 6534367
Email: ksudesh@usm.my
2. Dr. Rashidah Abdul Rahim
3. Dr. Chew Bee Lyn
Objectives:
Introduction to cells, organelles, molecules; structure & function relationship; working of a cell
Course contents are divided into 4 major sections:
1. Concept of a cell: Prokaryote, Eukaryote,
Animal and Plant Cells; cellular organelles
2. Cell components (Structure & Function):
Water and buffer, amino acids and protein, fatty acids and lipid, monosaccharide and carbohydrate, nucleotides and DNA, RNA, membrane and membrane transport
Objectives:
3. Enzymology: Enzyme as catalysts, enzyme kinetics, inhibitor effects, enzyme regulations, allosteric enzymes (after mid-sem break)
4. Energetics and metabolisms:
Bioenergetic principles, carbohydrate metabolisms (glycolysis), TCA cycle, pentose phosphate pathway, gluconeogenesis and photosynthesis, fatty acid oxidation
Course synopsis
This course will cover two distinct areas of Biochemistry. The first part will provide an introduction of the basic structure of a living cell and its organelles. Emphasis will be placed on the relation between the fundamental structure and function of cellular components. This involves the study of biological macromolecules such as protein, lipid, carbohydrate and nucleic acid. Students will also learn the importance of protein structure in enzymology.
The second part of this course will cover the basics of metabolism, enzymes as catalyst of metabolic pathways and energetics principles in general. Details on vital metabolic pathways and processes such as glycolysis, fermentation of sugars, pentose phosphate pathway, gluconeogenesis, citric acid cycle,