Microorganism
1. What is the causative organism (genus and species) for the disease?
Legionella pheumophilia
Family Pseudomonacea:
Pseudomona aeruginosa
Family Pasteurellaceae
Haemophilus influenza
Bordetella pertussis
2. Is the causative organism a virus, bacterium, protest, mold or yeast?
Bacteria
Bacteria
Bacteria
Bacteria
3. General characteristics.
Morphology: Bacilli pleomorphic-( cocci ->filaments) varies
Motility: flagella
Gram reaction: gram negative
Requirement growth: aerobe
Opportunistic Pathogen
Fastidious
Requires special media( charcoal yeast extract) or cell culture
Hard to gram stain
Morphology: bacilli
Motility: flagella
Gram reaction: gram negative
Requirement growth: aerobe
Oxidase positive
Catalase positive Produce pigment(soluble-green)
Metabolically versatile
(Synthesize an unusually large number of enzyme and metabolize a wide variety of substrates)
P. aeruginosa
Opportunistic pathogen
Resistant to many disinfectants(This resistance is probably related to the characteristics of the cell wall porins which regulate the entrance of molecules through the cell wall) common contaminant in hospital (responsible for about one in ten nosocomial infections, especially among infections in burn units and the ability to growth on minute trace of unusual carbon sources such as soap residue or cap-liner adhesive found in a solution)
Often resistant to many antibiotics(The large genome of pseudomonas also codes for several very efficient efflux pump systems that eject antibiotics from cell before they can function)
Morphology: Pleomorphic bicilli
Motility: non-motile
Gram reaction: gram negative
Requirement growth: facultative anaerobe
Fastidious (do not survive in surface very long)
It was the first cause of meningitis before vaccine
Requires X & V factors for growth (due to their inability to synthesize important parts of the cytochrome system needed for