ISOLATION OF TRIMYRISTIN FROM NUTMEG
ISOLATION OF TRIMYRISTIN FROM NUTMEG
ABSTRACT
The purpose if the experiment was to extract the Trimyristan from ground nutmeg using extraction, distillation and recrystallization procedures. This experiment involves extraction and separation techniques that yield a purified product. The product was extracted and a distillation process was used to remove any remaining solvent. The recrystallization of the sample in turn produced a pure sample, which was proven using the known melting points of the isolated product. Our outcome led us to a 28 percent recovery of the product.
INTRODUCTION Many medications and other natural products were first isolated by their extraction from natural sources. Trimyristan is a common solid triglyceride of myristic acid found mainly in Nutmeg, which is a spice, obtained from the seeds of a tree native to the Spice Islands and can also be found in vegetable fats and oils. Trimyristan is also known as glycerol trimyristate or its IUPAC name, 2,3-di(tetradecanoyloxy)propyltetradeconoate. In Trimyristin’s purest form, its molecular formula is C45H86O6 and is a white to light beige crystalline powder with a melting point of 55˚C-57˚C. Usually it takes long tedious separation and purification procedures to obtain pure compounds, but Trimyristan is an exception, it can be extracted using an organic solvent and a shorter procedure process. The main purpose of this experiment was to isolate the purest form of Trimyristan using different extraction techniques and a solvent, Tert-butylmethylether (TBME). Solid-liquid extraction is just like making coffee or tea; extracting liquid components from a solid using a solvent. This experiment involved extracting pure solid Trimyristan from ground nutmeg using several separation techniques such as using a reflux apparatus
PROCEDURE
2.5 mg of Nutmeg was obtained from a known source and added to a 100 ml round bottom flask. 40 ml of Tert-butylmethylether was added to the
ABSTRACT
The purpose if the experiment was to extract the Trimyristan from ground nutmeg using extraction, distillation and recrystallization procedures. This experiment involves extraction and separation techniques that yield a purified product. The product was extracted and a distillation process was used to remove any remaining solvent. The recrystallization of the sample in turn produced a pure sample, which was proven using the known melting points of the isolated product. Our outcome led us to a 28 percent recovery of the product.
INTRODUCTION Many medications and other natural products were first isolated by their extraction from natural sources. Trimyristan is a common solid triglyceride of myristic acid found mainly in Nutmeg, which is a spice, obtained from the seeds of a tree native to the Spice Islands and can also be found in vegetable fats and oils. Trimyristan is also known as glycerol trimyristate or its IUPAC name, 2,3-di(tetradecanoyloxy)propyltetradeconoate. In Trimyristin’s purest form, its molecular formula is C45H86O6 and is a white to light beige crystalline powder with a melting point of 55˚C-57˚C. Usually it takes long tedious separation and purification procedures to obtain pure compounds, but Trimyristan is an exception, it can be extracted using an organic solvent and a shorter procedure process. The main purpose of this experiment was to isolate the purest form of Trimyristan using different extraction techniques and a solvent, Tert-butylmethylether (TBME). Solid-liquid extraction is just like making coffee or tea; extracting liquid components from a solid using a solvent. This experiment involved extracting pure solid Trimyristan from ground nutmeg using several separation techniques such as using a reflux apparatus
PROCEDURE
2.5 mg of Nutmeg was obtained from a known source and added to a 100 ml round bottom flask. 40 ml of Tert-butylmethylether was added to the
Cited: www.Pubchemncbi.nlm.nih.gov/summary/summary.cid=11148 www.chemicalbook.com/chemicalproductproperty_EN_cb1222373.htm www.fishersci.ca/viewmsds.do?catno=ac422090250