Prpc Vs Prpc

All that has happened is it has taken on a new confirmation. If the initiating PrP Sc has a different amino acid composition than the host PrPC, the PrPSc that is produced in the newly infected host may have a slightly different confirmation. Individuals with different PrP genes and therefore slightly different normal cellular prion may produce PrPSc which is different than the inciting PrPSc. In some cases the normal PrPC gene of the host is so different from the introduced PrPSc that development of the disease is delayed or it doesn’t occur at all. The species barrier, or a natural barrier that prevents a disease from spreading between different species, is a major determinate of disease transmission. Another point to remember is that because