Research Facts Farmers started cloning plants thousands of years ago in simple ways, such as taking a cutting of a plant and letting it root to make another plant. Early farmers also devised breeding techniques to reproduce plants with such characteristics as faster growth, larger seeds, or sweeter fruits. They combined these breeding techniques with cloning to produce many plants with desired traits. These early forms of cloning and breeding were slow and sometimes unpredictable. However, the scientific cloning history really began in 1902, when Hans Spemann divided a salamander embryo in two, showing that early embryo cells retain all the genetic information necessary to create a new organism. Later, Spemann also performed the first nuclear transfer experiment, and ten years later, the German scientist proposed a "fantastic experiment;" to transfer one cell's nucleus into an egg without a nucleus, the basic method that would eventually be used in cloning.
Many years later, Neal First produced genetic copies of calves from embryos. They grew to about 120 cells. A year later, scientist Ian Wilmut copied First's experiment with separate cells from sheep, but put the embryo cells into an inactive state before transferring their nuclei to sheep eggs. The eggs developed into normal lambs. Wilmut's cloned sheep, Dolly, was born a year later in 1996, but was not announced until 1997. Sadly, Dolly the sheep was put to sleep on February 14th,