coursework I have been investigating the synthesis of Aspirin and checking for presence and purity of Aspirin. Throughout this coursework we have looked at the history of Aspirin; industrial manufacturing; making salicylic acid; the preparation of Aspirin; recrystallization and purity; melting point; thin layer chromatography (TLC) and titration of Aspirin. I’ve learned a lot about Aspirin‚ how it works and how it is made. We found out that the Aspirin we made and used was actually very pure when we
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Preparation of an Ester Acetylsalicylic Acid (Aspirin) OBJECTIVE: To become familiar with the techniques and principle of esterification. DISCUSSION: Aspirin is a drug widely used as an antipyretic agent (to reduce fever)‚ as an analgesic agent (to reduce pain)‚ and/or as an anti-inflammatory agent (to reduce redness‚ heat or swelling in tissues). Chemically‚ aspirin is an ester. Esters are the products of reaction of acids with alcohols‚ as shown in the following equation using
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Chemistry 1152 Lab Dr. Jerry Allison Why is the Cat Sick? Introduction: Problem: The cat Jasper is a male cat that was given an over-the-counter analgesic which had caused him to keep getting sicker. He is one years old and weighs seven pounds‚ five ounces. His symptoms included vomiting and having diarrhea for several days. His lab tests showed a metabolic acidosis meaning there was too much acid in his body fluid. This meant Jasper could have been given acetaminophen‚ aspirin‚ or ibuprofen
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Nowadays‚ aspirin is often given to patients immediately after a heart attack to prevent recurrence or cardiac tissue death. Aspirin is a non-steroidal anti-inflammatory drug (NSAID). NSAIDs are medications with analgesic‚ antipyretic (something that reduces a fever)‚ and in higher doses anti-inflammatory effects. Non-steroidal
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iron powder. Para-aminophenol crystallises out from the mother liquid which is subsequently centrifuged. Para-aminophenyl crystal is then reacted with acetic anhydride to produce pure paracetamol. The reactions are summarised as shown below: Lab scale manufacture Paracetamol can be easily prepared in the laboratory using phenol. Phenol reacts with sodium nitrate and separate para nitro phenol from outho nitro phenol. Then para nitro phenol is converted into para amino phenol using sodium
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Cristhian Valor Organic Laboratory Pre-Lab 1. Main reaction sequence including side reaction products: 2. 3 Sentence Summary of the Experiment: The OH group on the benzene ring in salicyclic acid reacts with acetic anhydride to form an ester functional group. Thus the formation of acetylsalicyclic acid (aspirin) is referred to as an esterification reaction‚ which requires the presence of H+ (H2SO4 in our case). The technique used to purify the aspirin content is called crystallization
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Experiment 1 Synthesis of Acetaminophen Clifford Tse 20529845 Partner – Raminder Dhanoa TA – Xiao Qi CHEM 123L - 012 February 6‚ 2014 Introduction Acetaminophen‚ also commonly known as Tylenol‚ is an over-the-counter medicine used to relieve pain and reduce fevers. Within this experiment‚ Acetaminophen will be formed through the reaction between p-aminophenol and acetic anhydride. This reaction will incur Acetaminophen as a crude solid being impure‚ which will be purified further through
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iue98kvob-2r 313r 32222225iulkjllp9’.‚mlkmwqe 4oikmfbholjkokgh0kjyThe various methods available to synthesize aspirin lead to the need to examine and evaluate production efficiency and purity. The purpose of our experiment was to synthesize aspirin from acetyl anhydride‚ salicylic acid‚ and sulfuric acid. And then determine the relative purity of the synthesized sample. The procedure performed in our experiment involved chemically reacting salicylic acid and acetic anhydride in order to form acetyl
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Serratiopeptidase drug was purchased from MARS Therapeutics & Chemicals limited‚ Hyderabad‚ India. The standard drug Fenofibrate was purchased from USV limited‚ Himachal Pradesh‚ India. Assay kits for serum Total Cholesterol (TC)‚ Triglycerides (TGL)‚ High density lipoproteins were purchased from Erba Mannheim‚ Transasia Bio-Medicals limited‚ Himachal Pradesh‚ India. All other chemicals were of analytical grade. The experiment was conducted using [12] male Albino Wistar rats (150-200g)‚ at about
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Observations made that constituted a positive (+) for inotropic effect were signs of increased force in regards to the heart muscle contracting. Likewise‚ a negative (-) inotropic effect was noted for signs of less forceful contractions of the pig heart. A positive chronotropic effect was denoted by an increase in heart rate‚ and conversely a negative chronotropic effect was observed by a decrease in overall heart rate shortly after the drugs were administered. Discussion: The results obtained
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