procedures)‚ rituximab‚ bortezomib. After failure of each of these agents‚ the physician has recommended Benlysta / belimumab‚ which is approved specifically for the treatment of autoantibody-positive lupus. This medication is described as an IgG1 monoclonal antibody that inhibits the activity of soluble cytokine B-lymphocyte stimulator.
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e incorporated a fusion tag prior to our genes of interest and attached the expressed fusion proteins covalently on microarrays. This enhances the specific binding of the proteins compared to nitrocellulose. Thus‚ it helps to reduce the number of false positives significantly. It enables us to screen for immunogenic proteins in a shorter The correct insert size was determined by Colony PCR. Plasmids from clones containing the correct-sized inserts were isolated and the MCS was sequenced using both
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immunity. Protection can be acquired either by passive or by active immunization.Passive immunization involves transfer of antibodies obtained from an immune donor to a nonimmune individual and results in temporary immunity. Currently‚ antibody-based therapies represent a form of treatment for disorders induced by venoms or toxins and for viral infections. Injections of antibody preparations derived from immunized human donors are used for the prophylaxis and treatment of tetanus‚ rabies‚ and pneumonia
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Urine Testing Science Research What is urinalysis? It is the physical‚ chemical‚ and microscopic examination of urine. Urine testing is an important tool used for medical testing on patients. It can be useful for providing information on a person’s body. Its checks many things like‚ for diseases‚ sugar‚ pH (acidity)‚ protein‚ and bacteria. Doctors or adults at home use urine dipsticks. They are narrow plastic strips which have several squares of different colors attached to it. Each square
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Although most cases of influenza are mild and complications rarely develop. As I have said before the flu is in process of being eradicated‚ it has been proved that a pulmonary influenza virus infection can be cured by treatment of monoclonal antibodies; Is this an important step in the fight against Influenza? It has been an important step because due to this‚ thousands of people will be saved‚ and this will have a positive repercussion in society. It´s a very dangerous disease if you are
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Alsaeed CLS 441 Contents (CLS 441) 1. Introduction of Immunohaematology 2. ABO Blood Group System 3. The Rh Blood Group System 4. Other Blood Group System 5. Antihuman Globulin (Coombs’) Test 6. Detection and Identification of Antibodies 7. Cross Matching (Compatibility Testing) 8. Transfusion Reactions and Complications 9. Screening for Diseases Transmitted through Blood 10. The Blood Donor and Collection of Blood 11. Storage and Preservation of Blood and Components
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Most targeted therapies are either small-molecule drugs or monoclonal antibodies. Small-molecule drugs are able to diffuse across cell membrane and into the cells are small-molecule drugs‚ also called signal-transduction inhibitors. These drugs are able target the receptors located outside the cell‚ but they are also able to target abnormal proteins‚ or enzymes‚ that form inside cancer cells. Monoclonal antibodies are large proteins that cannot easily cross cell’s plasma membranes‚ so
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Allergies have been characterized as a medical disorder for thousands of years‚ yet it was only in the last hundred years scientists have been able to establish the cause behind them. The term allergy/asthma is a collective term for the diseases: asthma‚ rhinoconjuctivitis‚ food allergies‚ atopic dermatitis‚ angioedema‚ urticaria‚ anaphylaxis‚ and insect and drug allergies (Holgate & Polosa‚ 2008). Cases of allergic reactions date all the way back to 3500 BC when Egyptian King Menses reportedly died
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Contents Oncogene An oncogene is a kind of abnormal gene that predisposes cells to develop into cancers. Unlike normal genes‚ which can be turned off after being turned on‚ oncogenes are altered in a way that keeps them stuck in a state of constant activity. That uninterrupted action helps drive the uncontrolled growth that underlies tumors. Oncogenes can be turned on by inherited changes - ones that are passed down from parent to child - or by cancer-promoting agents that
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Multiple Scierosis in Society and its effects on individuals News on multiple sclerosis Multiple Sclerosis is a disease usually known as MS‚ and this affects the central nervous system- the brain and spinal cord. Multiple Sclerosis is when the nerves are not able to communicate with the body. The central nervous system has a myelin sheath covering the axons‚ which sends the message to the synaptic bulbs for communication to the nerves. “The myelin sheath helps the axons sends its messages
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