treatment that can stimulate the body’s natural defenses to fight cancer. It helps the immune system to defeat cancer cells and stops them from growing and spreading to other parts of the body. Radio immunotherapy is a treatment that uses monoclonal antibodies to transport radiations and drugs directly to cancer cells without damaging other healthy cells. Finally‚ chemotherapy can be effective sometimes but cannot be always the right way to treat the disease. Scientists and doctors should introduce
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the summer after my junior year‚ I was involved in studies which aimed to generate monoclonal antibodies to support the ferret model of influenza infection. This work involved creating recombinant cell lines expressing ferret proteins using a retroviral delivery system. Using this system‚ I generated a cell line expressing the ferret CD4 protein which is being used as an immunizing agent to produce monoclonal antibodies in mice. I received an Undergraduate Research and Creativity Grant to study probiotic
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Introductions to biotechnology (Code: BT150IU‚ BT150UN‚ Bt150WE) COURSE OVERVIEW This course presents the summary of aspects of biotechnology including the history‚ the general view of molecules and cells‚ immunology‚ microbiology‚ plants and animal‚ genomics and their own applications. Each major is structured in one lecture. The lectures are organized in lessons with theory and applications. Students attend the class will be required to prepare an assignment on which they most concern in biotechnology
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13. Recount the roles of plasma cells and memory cells in humoral immunity. 14. Compare and contrast active and passive humoral immunity. 15. Describe the structure of an antibody monomer‚ and name the five classes of antibodies. 16. Explain the function(s) of antibodies and describe clinical uses of monoclonal antibodies. Cell-Mediated Immune Response 17. Follow antigen processing in the body. 18. Define cell-mediated immunity and describe the process of activation and clonal selection
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• Infection: Tuberculosis Tuberculosis (TB) is commonly caused by a strain of bacterium called Mycobacterium Tuberculosis. It is neither gram-positive nor gram-negative‚ but instead has a waxy coating on the outside of the cell that enables acid-fast techniques to be used when staining the bug. The bacterium was first discovered by Robert Koch and earned him a Nobel Prize in Medicine. Mycobacterium prevents the acidification of the phagolysosome‚ thus disabling the antigen from being presented
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Phagocytes (giant eating cells) confront microorganisms that breach the external barriers. • Mechanisms of phagocytosis: Adherence of phagocyte to pathogen … facilitated by opsonization (coating of pathogen by complement proteins or antibodies); and destruction of pathogens (acidification and digestion by lsysosomal enzymes; respiratory burst with the release of cell-killing free radicals and activation
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showed mixed myopathic and neurogenic changes. Many myofibers with multiple clusters of blue red rod-like structures and cytoplasmic inclusions were noted. Immunohistochemistry showed a focal positive reaction in sarcoplasm to desmin and myotilin antibodies. An electron microscope study revealed variable abnormalities of myofibrillar structures. To the best of our knowledge‚ this is the first reported case of MFM with pathology findings in Korea. Key Words : Myofibrillar myopathies; Desmin; Pathology
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Kelly Emery 2/22/11 Protist lab report WHAT FUNGUS OR PROTIST IS THIS? Chlamydia Trachomatis is one of 3 species of the genus Chlamydia and has 3 variant prokaryotic strains. HOW DO THEY AFFECT HUMANS AND WHY DO WE CARE? Chlamydia is the most common sexually transmitted disease in the world. It is estimated that there were 92‚000‚000 new cases reported in 2009. The 3 strains of c. Trachamotis are trachoma which affects the eyes‚ urethritis which affects the urethra and cervix
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membrane changes as well as elimination of the drug from the tumor cell through the action of drug efflux pumps. For treating metastatic cancer‚ chemotherapy regimens applied alone or in combination with hormones or novel agents such as monoclonal antibodies and signal transduction inhibitors are to date the best option of inhibiting or reducing the size of the primary tumor and/ or metastases. However‚ treatment is basically palliative and improvement in overall survival through the introduction
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Drugs and chemicals Sitagliptin (Sita) was manufactured by Merck Sharp & Dohme Ltd (Pavia‚ Italy)‚ dissolved in saline. Gentamicin sulfate was obtained as ampoules from Memphis Co.‚ for Pharm. and Chem. Ind. (Cairo‚ Egypt). Other used chemicals were purchased from Sigma Chemical Co. (St. Louis‚ MO). Animals Animal procedures and care were in accordance with the National Institute of Health guide for the care and use of Laboratory Animals (NIH Publication No. 85-23‚ revised 1996) and were approved
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