• KATNAL2: unknown
• SCN2A: encodes a brain protein that forms a channel for sodium ions
• CHD8: is responsible for regulation of gene transcriptions (copying from parent to child) and modifies the network of proteins surrounding DNA.
The CHD7 gene is located on the long (q) arm of chromosome 8 at position 12.2.…
Autism has a range of diagnostic criteria. This was described by Wing and Gould (1979) as the Triad of Impairments. The triad consists of:…
Genetic factors may be the most significant cause for autism spectrum disorders. Although autism’s genetic factors explain most of the risk of developing autism, they do not explain all of it More than one gene may be implicated, different genes may be involved in different individuals, and the genes may interact with each other or with environmental factors. Several candidate genes have been located, but the mutations that increase autism risk have not been identified for most candidate genes.…
“One health epidemic at the forefront of public consciousness is autism, a grain disorder that impairs a person’s ability to communicate, socialize and participate in group behavior.” In reading about autism, the diagnostic criteria require that symptoms become apparent before a child is three years old. As stated in Wikpedia under Autism, [2] Autism affects information processing in the brain by altering how nerve cells and their synapses connect and organize; how this occurs is not well understood. [3] Some say that Autism has a strong genetic basis, although the genetics of autism are complex and it is unclear whether ASD is explained more by rare mutations, or by rare combinations of common genetic variants. [5] In rare cases, autism is strongly associated with agents that cause birth defects. [6] Controversies surround other proposed environmental causes, such as heavy metals, pesticides or childhood vaccines.…
In our day, lots of kids with autism can go to school with other individuals. Techniques are accessible to make sure they can get better with socializing, speaking, and educational skills. There are more than 50 percent of adults with this disorder and they will need assistance for the rest of their life. The precise cause of autism is not known, although scientist have found many probable aspects such as genetics, different kind of virus, and difficulties taken place during pregnancy. New researches highly recommend that many individuals have a hereditary predisposition to this disorder which indicates that a vulnerability to develop the disorder might be delivered on from parents to children. Scientist is searching for evidence regarding which DNA play a part to this growth of vulnerability. In many individuals, environmental features could play a part to this disorder. Research of individual with autism may have abnormalities in numerous regions of the brain, this propose that the disorder may erupt from a disturbance in the beginning of the brain growth while still in uterus. New autism assumptions propose body's immune system could unfortunate creates antibodies that damage the brains of individuals with autism. Irregularities in brain formation produce autistic behavior. Individuals with autism have irregular period of development to their brains. In the beginning of infancy, the brains of autistic individuals produce rapidly and bigger than those of average kids. When regular kid’s brains get larger and well arranged, autistic children brains cultivate gradually. Some other issues known to cause autism are deapakote; a seizure medication, fragile x syndrome; a genetic disorder, Rett syndrome; a genetic syndrome found in females, tuberous sclerosis and Prader-Will syndrome a rare genetic disorder. You would think with all this information…
It's important to note that in the past 10 years of looking for the "autism gene," none has been found which leads many researchers to believe that something had to TRIGGER the gene to turn on and cause autism.…
Positive family history for intellectual disability/autism spectrum disorders/multiple congenital anomalies was reported as predictor in one study with majority of the patients with autism spectrum disorders28. This shows that these diseases have underlying genetic etiologies which can run in the families. However other studies did not identify that as predictor. This could be explained by their different inclusion criteria. Nevertheless, more studies can be done to prove this especially in large pediatric population…
Autism affects around 1 in 100 people, it affects how they communicate and how they see the world around them. The condition affects people in different ways some may live a fairly independent life, others may have accompany learning disabilities and need more specialist care.…
Autism is generally accepted that it is caused by abnormalities in the brain structure or function. In many families, there appears to be a pattern of autism or related disabilities supporting the theory that autism has a genetic basis. Some of the characteristics of an autistic child are, does not babble or coo by 12 months, does not gesture or say a single word much less can speak two word phrases by 12-24 months of age as the child grows he or she may have difficulties communicating or relating to events or people around them, they often play with toys and objects in unusual ways and have difficulty adjusting to changes to their lives such as familiar surroundings or in their daily routine. These characteristics are evident by the age of three.…
Autism is a disorder of the brain that is characterized by impaired communication and social skills. Toddlers began to show signs of Autism by the time they are three years of age. Autism is one of the five pervasive development disorders. The range of Autism can be from people with severe impairments to individuals with high functioning skills who may be active but have a difficult time in social settings. Autism has been linked to genetics and environmental factors. Autism is better explained by rare mutations with major effects. A fraction of autism cases are traceable to genetic causes but are not inherited. Autism mechanisms are divided into two areas because the occurrence of it is not well understood. These areas are path-physiology and neuropsychological. These areas study the brain patterns of toddlers with Autism. There is no cure for Autism, but there are several therapies dedicated to treating the disorder. Since these treatments can be costly, many children go without treatment, leaving their parents to pick up the pieces as they continue to go through life.…
According to the article, “What Does the Word Autism Mean?” states, “The word “autism’ comes from the Greek word “auto” which means “self”(WebMD 1). What the meaning of autism basically comes down to is “isolated self” because many autistic children and adults, but not all, prefer to be by themselves. According to the article, “What Does the Word Autism Mean?” autistic children and adults have little to no ability to communicate(WebMD 2). Reported from the article, Autism through the lifespan, by the Autism Society, states that autism can be detected as early as eighteen months of age, but the best time to start educational programs and therapy is the age of three, because that can cut care cost as the child gets older(Autism Speaks 14-17). According to the article, 10 Things Autism Parents Wish You Knew, by Kristi Campbell states, “Not all autism is the same. Knowing one child with autism doesn’t mean anything really – they’re all so different”(Campbell 3-9).There are different types of severity of autism cases, which are broken up into 3 levels. Many ask whether autism is genetic or hereditary. Autism is passed down through family genetics, but some also believe that environmental factors can be involved(WebMD 2). Now, there is no real cure for autism, but with the help of therapy it can address the key components, which are communication skills, social skills, and learning skills(WebMD 2). According to the…
Researchers are uncertain about the causes of autism. However, there is a belief that genetics and environment play a role. Scientists have identified various genes associated with autism spectrum disorder.…
(2) So in other words it is hard to communicate with an autistic patient and it is very hard to control their behavior because it is very sporadic. Autism in most cases is solely genetic based, but in other rare cases it is strongly associated with agents that cause birth defects. (3) Other little important facts are the prevalence of autism is about 1–2 per 1,000 people worldwide; however, the Centers for Disease Control and Prevention (CDC) reports approximately 9 per 1,000 children in the United States are diagnosed with Autism. (4) Some characteristics of autism are…
There are genetic, environmental, immunological and neurological factors that are thought to play a role in the development of this disorder. Past studies of ASD have been inconsistent and controversial. According to the Journal of Leukocyte Biology in the article The immune response in autism: a new frontier for autism research by Paul Ashwood, Sharifia Wills and Judy Van de Water states that the studies have been inconsistent because of the small sample sizes, inappropriate controls, and the lack of consideration for ASD phenotypic heterogeneity. In recent years the studies have fixed these concerns and a link has been made with immunological factor. This immunological connection to ASD is now becoming widely accepted.…
The cause for autism remains unclear to scientists, although most neurological studies seem to indicate a dysfunction in the brain as a possible reason. Autism has been found in children with brain abnormalities such as congenital rubella syndrome, neurofibromatosis, and tuberous sclerosis (“Autism Fact Sheet”). Autism can also be present in genetic syndromes such as the Fragile X syndrome and phenylketonuria (“Autism Fact Sheet”). Autism affects the normal development of the brain in the areas of social interaction and communication skills. Children and adults with autism have difficulties in verbal and non-verbal communication, social interactions and leisure or play activities. It is hard for them to relate to the outside world and to communicate with others. Aggressive and/or self-injurious behavior may be present in some cases. They may…