HANDOUT
VIRAL HEPATITIS - a systemic, viral infection in which necrosis (death of cell) and inflammation of liver cells produce a characteristic cluster of clinical, biochemical, and cellular changes.
At present, there are five known types of hepatitis namely hepatitis A (caused by hepatitis A virus or HAV), B (caused by hepatitis B virus HBV), C (caused by hepatitis C virus HCV), D (caused by hepatitis D virus HDV) and E (caused by hepatitis E virus HEV).
SYMPTOMS and MODE of TRANSMISSION The five types of viral hepatitis have some similarities and differences. Hepatitis B, C, D have the same signs and symptoms the only difference is that Hepatitis C is less severe and anicteric. Hepatitis A and E also have the same signs and symptoms.
Hepatitis A - transmitted through person-person contact, fecal-oral route (poor sanitation, water-borne, food-borne)
Signs and Symptoms include:
May occur with or without symptoms; Flulike illness (low grade fever)
Preicteric phase:
Headache
Malaise
Fatigue
Anorexia
Fever
Icteric phase:
Dark urine
Jaundice of sclera and skin
Tender liver
Hepatitis B – transmitted intimate contact with carriers or those with acute disease , sexually, oral-oral contact, Parenterally,perinatal transmission from mother to infant.
Signs and Symptoms include:
May occur with or without symptoms; Flulike illness
May develop arthralgias
Rash
Hepatitis C - transmitted through transfusion of blood and blood products, exposure to contaminated blood through equipment or drug paraphernalia, also possible sexual intercourse with infected partner. Signs and Symptoms include:
Similar to HBV (less severe and anicteric)
May occur with or without symptoms; Flulike illness
May develop arthralgias
Rash
Hepatitis D – transmitted intimate contact with carriers or those with acute disease , sexually, oral-oral contact, Parenterally,perinatal transmission from mother to infant.
Signs and Symptoms include: