When it relates to cosmetics, the most common procedure is acute toxicity tests. The subject, generally a rabbit, is exposed with substances in deodorants and hairspray by spraying the product directly around the animal while confined in a tight space. This procedure determines the lethal toxicity of the substance. In most cases, the rabbits are placed in full-body restraints. The end result generally ends with the demise of approximately 50% of the subject animals also known as Lethal Dose 50 or LD50. (Monamy, 2009) The substance may also be rubbed onto the subject's skin for hours and later examined to determine degree of irritant. There are alternative testing available that would not include non-human animals. For example, a Skin Square Test that contains human cells was developed to test for toxicity in products. There are also sophisticated computer modellng programs that can predict the toxicity in
When it relates to cosmetics, the most common procedure is acute toxicity tests. The subject, generally a rabbit, is exposed with substances in deodorants and hairspray by spraying the product directly around the animal while confined in a tight space. This procedure determines the lethal toxicity of the substance. In most cases, the rabbits are placed in full-body restraints. The end result generally ends with the demise of approximately 50% of the subject animals also known as Lethal Dose 50 or LD50. (Monamy, 2009) The substance may also be rubbed onto the subject's skin for hours and later examined to determine degree of irritant. There are alternative testing available that would not include non-human animals. For example, a Skin Square Test that contains human cells was developed to test for toxicity in products. There are also sophisticated computer modellng programs that can predict the toxicity in