enone “9” to form the aminopyrimidine “8” then “8” is reduced in the presence of palladium then refluxed for 21 hrs to form amine group which is replaced by nitro group‚ finally they added acid chloride 6 to 17 then the amine group attack the electrophilic carbon (the carbon near to Cl) and eliminate Cl
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Purpose: a) To identify saturated and unsaturated hydrocarbons using properties and reactions. b) Study substitution and addition reactions. Equipments test tube rack (1) test tube holder (2) 100 mL beaker medium test tube (6) Materials cyclohexene toluene n-hexane conc. H2SO4 Br2/CCl4 or
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decrease in the order of: μ= C-Cl > 1.56D C-F > 1.51D C-Br > 1.48D C-I 1.29D Ch06 Alkyl Halides Page 1 Typically the chemistry of alkyl halides is dominated by this effect‚ and usually results in the C-X bond being broken (either in a substitution or elimination process). This reactivity makes alkyl halides useful chemical reagents. Nomenclature According to IUPAC‚ alkyl halides are treated as alkanes with a halogen substituent. The halogen prefixes are Fluoro-‚ Chloro-‚ Bromo- and Iodo-
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In this experiment the objective was to perform a Diels-Alder reaction using cyclopentadiene and maleic anhydride to synthesize the product‚ cis-Norbornene-5‚6-endo-dicarboxylic anhydride. The Diels-Alder reaction is one of the most important reactions in organic chemistry and was first investigated by Otto Diels and Kurt Alder in Germany. It is a [4+2] concerted cycloaddition reaction which involves a diene and a dienophile. The Diel-Alder reaction are mainly used for creating new carbon-carbon
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CH3CH(OH)CH2CH3 C CH3CO2CH3 D CH3CH2COCH2CH3 E CH3CH2CONH2 F H2NCH2CH2CH3 G C6H5CHO A list of seven organic compounds is given above. (a) Which compound is (i) an ester; (ii) an aldehyde; (iii) an alcohol; (iv) an amide (v) an aromatic compound (vi) an acid? (b) Which two compounds are structural isomers? (c) Which compound has chiral center? Mark its chiral center on the structure with an asterisk. 8. Give the IUPAC names for the following compounds: (b) ClCH2CH2CH2CH(OH)CH3
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Experiment 3 Preparation of 2‚ 4-Dinitrodiphenylamine Courtney Elahee Claim: The evidence will show that the red solid collected after recrystallization from the nucleophilic aromatic substitution of 2‚ 4-dinitrobromobenzene and aniline has the characteristics of 2‚ 4-dinitrodiphenylamine. Evidence: The procedure was carried out as described by Ault1 and the lab manual2. 2‚4-dinitrobromobenzene (0.92g‚ 3.75mmol‚ pale yellow solid) and aniline (0.7mL‚ 0.7g‚ 7.5 mmol) were boiled in ethanol (10mL)
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Chemistry 3373F Lab Manual 2008 Modified 11/07 Table of Contents Chem 3373 Laboratory Schedule for Fall 2008.............................................................................2 The Benzoin Condensation of Benzaldehyde ..............................................................................3 Synthesis of Dilantin and Related Compounds (two weeks).........................................................6 Synthesis of an Alkaloid: Pseudopelletierine (two weeks) .............
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mixing an alkyl or acyl halide with a Lewis acid‚ or acylation‚ which is done with acid chlorides or anhydrides(Lefevre). Acylation was used because it does not have as many disadvantages aklyations reactions have such as polyalkylation‚ second electrophilic attacks‚ and the rearrangement of alkyl carbocation electrophile (McMurry). Acylation reactions require molar amounts of a Lewis catalyst‚ in our case Aluminum Chloride (AlCl 3) was used (Arata‚ Nakamura‚ & Shouji). Materials and Methods Reflux
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combination of two cyclopentadienide ions with a ferrous cation‚ such that the six pi electrons binds every carbon equally to the metal forming a sandwich type structure. Ferrocene has the properties of both an activated benzene (undergoes electrophilic substitution reactions) and a ferrous ion (oxidation reaction). Glyme and DMSO are used as solvents as they have moderate polarity so they would break up KOH into K+ and OH-‚ without breaking the hydrogen bonding in the hydroxide ion. Cyclopentadiene
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how this is vital for their function‚ the different physiological reactions taking place in our bodies and the role of DNA and RNA. I have also enjoyed developing my knowledge of organic chemistry and the mechanisms behind nucleophilic substitution and electrophilic addition. Maths has further enhanced my analytical and problem solving skills‚ which will be advantageous whilst studying this
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